Quick answer
- Winner
- San Francisco 49ers
- Final score
- San Francisco 49ers 48–27 Indianapolis Colts
- Halftime
- San Francisco 49ers 30–17 Indianapolis Colts at halftime
- FantasyHQ MVP
- Brock Purdy
- Top passer
- Philip Rivers
- Biggest EPA play
- (3:38) (No Huddle, Shotgun) 17-P.Rivers pass short middle intended for 84-T.Warren INTERCE…
- Game date
- 2025-12-22
Game summary
The San Francisco 49ers beat the Indianapolis Colts 48–27 on 2025-12-22. Brock Purdy posted a game-high +20.36 total EPA in the passing.
The highest-scoring period was Q1 with 27 combined points.
Line score
Final score and points by quarter.
| Q1 | Q2 | Q3 | Q4 | — | T | |
|---|---|---|---|---|---|---|
 San Francisco 49ers | 20 | 10 | 10 | 14 | 0 | 48 |
 Indianapolis Colts | 7 | 10 | 3 | 7 | 0 | 27 |
Scoring Map
Each pin marks where a score occurred on the field — yard line from play-by-play.
SFSan Francisco 49ers
(10:36) (Shotgun) 17-P.Rivers pass deep middle to 14-A.Pierce for 20 yards, TOUCHDOWN. Penalty on SF-96-C.Ferrell, Defensive Offside, declined.
10-B.Grupe extra point is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.
(7:19) (Shotgun) 13-B.Purdy pass deep middle to 5-D.Robinson for 22 yards, TOUCHDOWN.
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
(4:37) (Shotgun) 13-B.Purdy pass short right to 23-C.McCaffrey for 2 yards, TOUCHDOWN.
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
(14:19) (Shotgun) 17-P.Rivers pass deep middle to 14-A.Pierce for 16 yards, TOUCHDOWN. Penalty on SF-28-D.Luter, Defensive Pass Interference, declined.
10-B.Grupe extra point is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.
(9:42) 13-B.Purdy pass short right to 85-G.Kittle for 11 yards, TOUCHDOWN.
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
(1:55) 18-E.Pineiro 25 yard field goal is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
(:21) 10-B.Grupe 39 yard field goal is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.
(11:02) (Shotgun) 13-B.Purdy pass short right to 15-J.Jennings for 3 yards, TOUCHDOWN.
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
(8:21) 10-B.Grupe 51 yard field goal is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.
(4:07) 18-E.Pineiro 38 yard field goal is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
(12:45) (Shotgun) 28-J.Taylor up the middle for 1 yard, TOUCHDOWN.
10-B.Grupe extra point is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.
(7:42) (Shotgun) 13-B.Purdy pass short left to 23-C.McCaffrey for 9 yards, TOUCHDOWN.
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
(3:38) (No Huddle, Shotgun) 17-P.Rivers pass short middle intended for 84-T.Warren INTERCEPTED by 53-D.Winters at SF 26. 53-D.Winters for 74 yards, TOUCHDOWN.
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
INDIndianapolis ColtsFantasyHQ Analytics
Scoring timeline
Chronological scoring plays — scroll to follow the game.
- INDIndianapolis Colts
Q1 10:36TD Artavis PiercePoints+6
- Yard line
- SF 20
- Score
- 0-6
(10:36) (Shotgun) 17-P.Rivers pass deep middle to 14-A.Pierce for 20 yards, TOUCHDOWN. Penalty on SF-96-C.Ferrell, Defensive Offside, declined.
- INDIndianapolis Colts
Q1 10:31XP Blake GrupePoints+1
- Yard line
- SF 15
- Score
- 0-7
10-B.Grupe extra point is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.
- SFSan Francisco 49ers
Q1 7:19TD Dominique RobinsonPoints+6
- Yard line
- IND 22
- Score
- 6-7
(7:19) (Shotgun) 13-B.Purdy pass deep middle to 5-D.Robinson for 22 yards, TOUCHDOWN.
- SFSan Francisco 49ers
Q1 7:14XP Eddy PineiroPoints+1
- Yard line
- IND 15
- Score
- 7-7
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
- SFSan Francisco 49ers
Q1 4:37TD Christian McCaffreyPoints+6
- Yard line
- IND 2
- Score
- 13-7
(4:37) (Shotgun) 13-B.Purdy pass short right to 23-C.McCaffrey for 2 yards, TOUCHDOWN.
- SFSan Francisco 49ers
Q1 4:33TD Eddy PineiroPoints+7
- Yard line
- IND 15
- Score
- 14-7
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
- INDIndianapolis Colts
Q2 14:19TD Artavis PiercePoints+6
- Yard line
- SF 16
- Score
- 14-13
(14:19) (Shotgun) 17-P.Rivers pass deep middle to 14-A.Pierce for 16 yards, TOUCHDOWN. Penalty on SF-28-D.Luter, Defensive Pass Interference, declined.
- INDIndianapolis Colts
Q2 14:15XP Blake GrupePoints+1
- Yard line
- SF 15
- Score
- 14-14
10-B.Grupe extra point is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.
- SFSan Francisco 49ers
Q2 9:42TD George KittlePoints+6
- Yard line
- IND 11
- Score
- 20-14
(9:42) 13-B.Purdy pass short right to 85-G.Kittle for 11 yards, TOUCHDOWN.
- SFSan Francisco 49ers
Q2 9:36XP Eddy PineiroPoints+1
- Yard line
- IND 15
- Score
- 21-14
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
- SFSan Francisco 49ers
Q2 1:55FG Eddy PineiroPoints+3
- Yard line
- IND 7
- Score
- 24-14
(1:55) 18-E.Pineiro 25 yard field goal is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
- INDIndianapolis Colts
Q2 0:21FG Blake GrupePoints+3
- Yard line
- SF 21
- Score
- 24-17
(:21) 10-B.Grupe 39 yard field goal is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.
- SFSan Francisco 49ers
Q3 11:02TD Jauan JenningsPoints+6
- Yard line
- IND 3
- Score
- 30-17
(11:02) (Shotgun) 13-B.Purdy pass short right to 15-J.Jennings for 3 yards, TOUCHDOWN.
- SFSan Francisco 49ers
Q3 10:58XP Eddy PineiroPoints+1
- Yard line
- IND 15
- Score
- 31-17
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
- INDIndianapolis Colts
Q3 8:21FG Blake GrupePoints+3
- Yard line
- SF 33
- Score
- 31-20
(8:21) 10-B.Grupe 51 yard field goal is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.
- SFSan Francisco 49ers
Q3 4:07FG Eddy PineiroPoints+3
- Yard line
- IND 19
- Score
- 34-20
(4:07) 18-E.Pineiro 38 yard field goal is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
- INDIndianapolis Colts
Q4 12:45TD Jawaan TaylorPoints+6
- Yard line
- SF 1
- Score
- 34-26
(12:45) (Shotgun) 28-J.Taylor up the middle for 1 yard, TOUCHDOWN.
- INDIndianapolis Colts
Q4 12:41XP Blake GrupePoints+1
- Yard line
- SF 15
- Score
- 34-27
10-B.Grupe extra point is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.
- SFSan Francisco 49ers
Q4 7:42TD Christian McCaffreyPoints+6
- Yard line
- IND 9
- Score
- 40-27
(7:42) (Shotgun) 13-B.Purdy pass short left to 23-C.McCaffrey for 9 yards, TOUCHDOWN.
- SFSan Francisco 49ers
Q4 7:37XP Eddy PineiroPoints+1
- Yard line
- IND 15
- Score
- 41-27
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
- SFSan Francisco 49ers
Q4 3:38TD Dee WintersPoints+6
- Yard line
- SF 29
- Score
- 47-27
(3:38) (No Huddle, Shotgun) 17-P.Rivers pass short middle intended for 84-T.Warren INTERCEPTED by 53-D.Winters at SF 26. 53-D.Winters for 74 yards, TOUCHDOWN.
- SFSan Francisco 49ers
Q4 3:26XP Eddy PineiroPoints+1
- Yard line
- IND 15
- Score
- 48-27
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
Stars of the game
Top performers by total expected points added (EPA).
- 1
Brock Purdy · San Francisco 49ers · Passing · +20.36 total EPA · 36 snaps · +0.57 EPA/play - 2George Kittle · San Francisco 49ers · Receiving · +9.77 total EPA · 8 snaps · +1.22 EPA/play
- 3Artavis Pierce · Indianapolis Colts · Receiving · +9.64 total EPA · 4 snaps · +2.41 EPA/play
- 4Jauan Jennings · San Francisco 49ers · Receiving · +9.05 total EPA · 6 snaps · +1.51 EPA/play
- 5Philip Rivers · Indianapolis Colts · Passing · +3.67 total EPA · 39 snaps · +0.09 EPA/play
- 6
Josh Downs · Indianapolis Colts · Receiving · +3.27 total EPA · 9 snaps · +0.36 EPA/play - 7Christian McCaffrey · San Francisco 49ers · Receiving · +3.16 total EPA · 8 snaps · +0.40 EPA/play
- 8Jawaan Taylor · Indianapolis Colts · Receiving · +3.07 total EPA · 3 snaps · +1.02 EPA/play
FantasyHQ Game MVP
Highest total EPA with the player's top snap and the game's biggest single play when different.
FantasyHQ Game MVP
Brock Purdy — SF · Passing
Brock Purdy posted the highest total EPA (+20.36) in the game, the strongest overall impact for San Francisco 49ers. Across 36 counted snaps, they averaged +0.57 EPA per play.
Brock Purdy's top snap (-4.18 EPA): (4:47) 13-B.Purdy pass short middle intended for 84-K.Bourne INTERCEPTED by 0-C.Bynum at IND 21. 0-C.Bynum to IND 29 for 8 yards (88-J.Tonges).
Biggest single play (-10.59 EPA): Philip Rivers — (3:38) (No Huddle, Shotgun) 17-P.Rivers pass short middle intended for 84-T.Warren INTERCEPTED by 53-D.Winters at SF 26. 53-D.Winters for 74 yards, TOUCHDOWN.
Quarterback report card
Philip Rivers led all passers in efficiency for Indianapolis Colts, setting the tone in the passing game according to FantasyHQ analytics.
- Philip Rivers (Indianapolis Colts) · 39 dropbacks · 59.0% completion · -1.2% CPOE · +0.09 EPA/play · +3.67 total EPA
- Brock Purdy (San Francisco 49ers) · 36 dropbacks · 69.4% completion · +12.4% CPOE · +0.57 EPA/play · +20.36 total EPA
Team stats comparison
Side-by-side offensive and defensive efficiency.
| Stat | San Francisco 49ers | Indianapolis Colts |
|---|---|---|
| Offensive EPA/play | +0.297 | -0.063 |
| Offensive success rate | 58.0% | 51.2% |
| Pass EPA/play | +0.566 | +0.010 |
| Rush EPA/play | +0.186 | -0.088 |
| Defensive EPA/play | +0.063 | -0.297 |
| Defensive success rate | 48.8% | 42.0% |
Drive & efficiency notes
Despite the final score, San Francisco 49ers generated the better offensive EPA per play (+0.30 vs -0.06), suggesting they moved the ball more efficiently.
Season benchmark context (offensive EPA per play):
- San Francisco 49ers: +0.30 EPA/play (97th percentile vs. 2025 team-game averages)
- Indianapolis Colts: -0.06 EPA/play (32nd percentile vs. 2025 team-game averages)
- Indianapolis Colts: 10 drives, -5.03 total EPA, 6 scoring drives
- San Francisco 49ers: 11 drives, +24.03 total EPA, 7 scoring drives
Who scored touchdowns and field goals
Every touchdown and field goal from official play-by-play.
Touchdowns
- Indianapolis Colts — Artavis Pierce (Philip Rivers pass)
- San Francisco 49ers — Dominique Robinson (Brock Purdy pass)
- San Francisco 49ers — Christian McCaffrey (Brock Purdy pass)
- Indianapolis Colts — Artavis Pierce (Philip Rivers pass)
- San Francisco 49ers — George Kittle (Brock Purdy pass)
- San Francisco 49ers — Jauan Jennings (Brock Purdy pass)
- Indianapolis Colts — Jawaan Taylor
- San Francisco 49ers — Christian McCaffrey (Brock Purdy pass)
- San Francisco 49ers — Dee Winters
Field goals
- San Francisco 49ers — Eddy Pineiro
- Indianapolis Colts — Blake Grupe
- Indianapolis Colts — Blake Grupe
- San Francisco 49ers — Eddy Pineiro
Quarter by quarter
Quarter-by-quarter recap from live scoring plays.
The opening quarter: San Francisco 49ers won the period 20–7. Indianapolis Colts found the end zone from the SF 20 (Q1 10:36); Indianapolis Colts added 1 points from the SF 15 (Q1 10:31) — 10-B.Grupe extra point is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.; San Francisco 49ers found the end zone from the IND 22 (Q1 7:19) — (7:19) (Shotgun) 13-B.Purdy pass deep middle to 5-D.Robinson for 22 yards, TOUCHDOWN.; San Francisco 49ers added 1 points from the IND 15 (Q1 7:14) — 18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.; San Francisco 49ers found the end zone from the IND 2 (Q1 4:37) — (4:37) (Shotgun) 13-B.Purdy pass short right to 23-C.McCaffrey for 2 yards, TOUCHDOWN.; San Francisco 49ers found the end zone from the IND 15 (Q1 4:33) — 18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead..
The second quarter: The quarter finished even at 10–10. Indianapolis Colts found the end zone from the SF 16 (Q2 14:19); Indianapolis Colts added 1 points from the SF 15 (Q2 14:15) — 10-B.Grupe extra point is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.; San Francisco 49ers found the end zone from the IND 11 (Q2 9:42) — (9:42) 13-B.Purdy pass short right to 85-G.Kittle for 11 yards, TOUCHDOWN.; San Francisco 49ers added 1 points from the IND 15 (Q2 9:36) — 18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.; San Francisco 49ers connected on a field goal from the IND 7 (Q2 1:55) — (1:55) 18-E.Pineiro 25 yard field goal is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.; Indianapolis Colts connected on a field goal from the SF 21 (Q2 0:21) — (:21) 10-B.Grupe 39 yard field goal is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez..
The third quarter: San Francisco 49ers won the period 10–3. San Francisco 49ers found the end zone from the IND 3 (Q3 11:02) — (11:02) (Shotgun) 13-B.Purdy pass short right to 15-J.Jennings for 3 yards, TOUCHDOWN.; San Francisco 49ers added 1 points from the IND 15 (Q3 10:58) — 18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.; Indianapolis Colts connected on a field goal from the SF 33 (Q3 8:21) — (8:21) 10-B.Grupe 51 yard field goal is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.; San Francisco 49ers connected on a field goal from the IND 19 (Q3 4:07) — (4:07) 18-E.Pineiro 38 yard field goal is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead..
The fourth quarter: San Francisco 49ers won the period 14–7. Indianapolis Colts found the end zone from the SF 1 (Q4 12:45) — (12:45) (Shotgun) 28-J.Taylor up the middle for 1 yard, TOUCHDOWN.; Indianapolis Colts added 1 points from the SF 15 (Q4 12:41) — 10-B.Grupe extra point is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.; San Francisco 49ers found the end zone from the IND 9 (Q4 7:42) — (7:42) (Shotgun) 13-B.Purdy pass short left to 23-C.McCaffrey for 9 yards, TOUCHDOWN.; San Francisco 49ers added 1 points from the IND 15 (Q4 7:37) — 18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.; San Francisco 49ers found the end zone from the SF 29 (Q4 3:38); San Francisco 49ers added 1 points from the IND 15 (Q4 3:26) — 18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead..
Turning points
Plays that moved win probability the most.
- Indianapolis Colts (Q1 7:14) — 18-E.Pineiro kicks 56 yards from SF 35 to IND 9. 26-A.Abdullah to IND 27 for 18 yards (27-J.Brown). FUMBLES (27-J.Brown), RECOVERED by SF-88-J.Tonges at IND 26.
- Indianapolis Colts (Q2 14:19) — (14:19) (Shotgun) 17-P.Rivers pass deep middle to 14-A.Pierce for 16 yards, TOUCHDOWN. Penalty on SF-28-D.Luter, Defensive Pass Interference, declined.
- Indianapolis Colts (Q1 11:45) — (11:45) (Shotgun) 17-P.Rivers pass short right to 2-J.Downs to SF 23 for 13 yards (20-U.Stout).
- San Francisco 49ers (Q3 13:09) — (13:09) (Shotgun) 13-B.Purdy pass short right to 15-J.Jennings pushed ob at IND 26 for 21 yards (29-M.Blackmon).
- Indianapolis Colts (Q1 14:14) — (14:14) (Shotgun) 17-P.Rivers pass short middle to 28-J.Taylor to IND 49 for 19 yards (6-M.Mustapha).
Impact plays
Highest EPA snaps that flipped field position.
- Indianapolis Colts (Q4 3:38) — (3:38) (No Huddle, Shotgun) 17-P.Rivers pass short middle intended for 84-T.Warren INTERCEPTED by 53-D.Winters at SF 26. 53-D.Winters for 74 yards, TOUCHDOWN.
- Indianapolis Colts (Q1 7:14) — 18-E.Pineiro kicks 56 yards from SF 35 to IND 9. 26-A.Abdullah to IND 27 for 18 yards (27-J.Brown). FUMBLES (27-J.Brown), RECOVERED by SF-88-J.Tonges at IND 26.
- San Francisco 49ers (Q4 4:47) — (4:47) 13-B.Purdy pass short middle intended for 84-K.Bourne INTERCEPTED by 0-C.Bynum at IND 21. 0-C.Bynum to IND 29 for 8 yards (88-J.Tonges).
- Indianapolis Colts (Q2 14:19) — (14:19) (Shotgun) 17-P.Rivers pass deep middle to 14-A.Pierce for 16 yards, TOUCHDOWN. Penalty on SF-28-D.Luter, Defensive Pass Interference, declined.
Every scoring play
Chronological scoring with play-by-play context.
- Indianapolis Colts TD (+6) — Q1 10:36 · SF 20 · Score 0-6
(10:36) (Shotgun) 17-P.Rivers pass deep middle to 14-A.Pierce for 20 yards, TOUCHDOWN. Penalty on SF-96-C.Ferrell, Defensive Offside, declined. - Indianapolis Colts XP (+1) — Q1 10:31 · SF 15 · Score 0-7
10-B.Grupe extra point is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez. - San Francisco 49ers TD (+6) — Q1 7:19 · IND 22 · Score 6-7
(7:19) (Shotgun) 13-B.Purdy pass deep middle to 5-D.Robinson for 22 yards, TOUCHDOWN. - San Francisco 49ers XP (+1) — Q1 7:14 · IND 15 · Score 7-7
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead. - San Francisco 49ers TD (+6) — Q1 4:37 · IND 2 · Score 13-7
(4:37) (Shotgun) 13-B.Purdy pass short right to 23-C.McCaffrey for 2 yards, TOUCHDOWN. - San Francisco 49ers TD (+7) — Q1 4:33 · IND 15 · Score 14-7
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead. - Indianapolis Colts TD (+6) — Q2 14:19 · SF 16 · Score 14-13
(14:19) (Shotgun) 17-P.Rivers pass deep middle to 14-A.Pierce for 16 yards, TOUCHDOWN. Penalty on SF-28-D.Luter, Defensive Pass Interference, declined. - Indianapolis Colts XP (+1) — Q2 14:15 · SF 15 · Score 14-14
10-B.Grupe extra point is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez. - San Francisco 49ers TD (+6) — Q2 9:42 · IND 11 · Score 20-14
(9:42) 13-B.Purdy pass short right to 85-G.Kittle for 11 yards, TOUCHDOWN. - San Francisco 49ers XP (+1) — Q2 9:36 · IND 15 · Score 21-14
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead. - San Francisco 49ers FG (+3) — Q2 1:55 · IND 7 · Score 24-14
(1:55) 18-E.Pineiro 25 yard field goal is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead. - Indianapolis Colts FG (+3) — Q2 0:21 · SF 21 · Score 24-17
(:21) 10-B.Grupe 39 yard field goal is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez. - San Francisco 49ers TD (+6) — Q3 11:02 · IND 3 · Score 30-17
(11:02) (Shotgun) 13-B.Purdy pass short right to 15-J.Jennings for 3 yards, TOUCHDOWN. - San Francisco 49ers XP (+1) — Q3 10:58 · IND 15 · Score 31-17
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead. - Indianapolis Colts FG (+3) — Q3 8:21 · SF 33 · Score 31-20
(8:21) 10-B.Grupe 51 yard field goal is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez. - San Francisco 49ers FG (+3) — Q3 4:07 · IND 19 · Score 34-20
(4:07) 18-E.Pineiro 38 yard field goal is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead. - Indianapolis Colts TD (+6) — Q4 12:45 · SF 1 · Score 34-26
(12:45) (Shotgun) 28-J.Taylor up the middle for 1 yard, TOUCHDOWN. - Indianapolis Colts XP (+1) — Q4 12:41 · SF 15 · Score 34-27
10-B.Grupe extra point is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez. - San Francisco 49ers TD (+6) — Q4 7:42 · IND 9 · Score 40-27
(7:42) (Shotgun) 13-B.Purdy pass short left to 23-C.McCaffrey for 9 yards, TOUCHDOWN. - San Francisco 49ers XP (+1) — Q4 7:37 · IND 15 · Score 41-27
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead. - San Francisco 49ers TD (+6) — Q4 3:38 · SF 29 · Score 47-27
(3:38) (No Huddle, Shotgun) 17-P.Rivers pass short middle intended for 84-T.Warren INTERCEPTED by 53-D.Winters at SF 26. 53-D.Winters for 74 yards, TOUCHDOWN. - San Francisco 49ers XP (+1) — Q4 3:26 · IND 15 · Score 48-27
18-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
Key takeaways
What to remember for fantasy research and follow-up box score digging.
- San Francisco 49ers earned the result — use the box score for snap-level context.
- Brock Purdy (San Francisco 49ers) led total EPA — start here for highlight and prop research.
- Brock Purdy (SF) finished above expected through the air (positive CPOE).
Frequently asked questions
Who won San Francisco 49ers vs Indianapolis Colts on 2025-12-22?
The San Francisco 49ers beat the Indianapolis Colts 48-27 in Week 16, 2025.
What was the score by quarter in San Francisco 49ers vs Indianapolis Colts?
Q1: San Francisco 49ers 20, Indianapolis Colts 7; Q2: San Francisco 49ers 10, Indianapolis Colts 10; Q3: San Francisco 49ers 10, Indianapolis Colts 3; Q4: San Francisco 49ers 14, Indianapolis Colts 7; Final: San Francisco 49ers 48, Indianapolis Colts 27.
Who scored touchdowns and field goals in San Francisco 49ers vs Indianapolis Colts?
Indianapolis Colts touchdown — A. Pierce (P. Rivers pass) (Q1 10:36) San Francisco 49ers touchdown — D. Robinson (B. Purdy pass) (Q1 7:19) San Francisco 49ers touchdown — C. McCaffrey (B. Purdy pass) (Q1 4:37) Indianapolis Colts touchdown — A. Pierce (P. Rivers pass) (Q2 14:19) San Francisco 49ers touchdown — G. Kittle (B. Purdy pass) (Q2 9:42) San Francisco 49ers touchdown — J. Jennings (B. Purdy pass) (Q3 11:02) Indianapolis Colts touchdown — J. Taylor (Q4 12:45) San Francisco 49ers touchdown — C. McCaffrey (B. Purdy pass) (Q4 7:42) San Francisco 49ers touchdown — D. Winters (Q4 3:38) San Francisco 49ers field goal — E. Pineiro (Q2 1:55, 3 pts) Indianapolis Colts field goal — B. Grupe (Q2 0:21, 3 pts) Indianapolis Colts field goal — B. Grupe (Q3 8:21, 3 pts) San Francisco 49ers field goal — E. Pineiro (Q3 4:07, 3 pts) Extra points followed each touchdown unless noted in the play-by-play.
How did the quarterbacks play in San Francisco 49ers vs Indianapolis Colts?
Philip Rivers (Indianapolis Colts), 59.0% completion, -1.2% CPOE, +0.09 EPA per dropback, +3.67 total passing EPA. Brock Purdy (San Francisco 49ers), 69.4% completion, +12.4% CPOE, +0.57 EPA per dropback, +20.36 total passing EPA.
Who was FantasyHQ's player of the game in San Francisco 49ers vs Indianapolis Colts?
Brock Purdy (San Francisco 49ers) was FantasyHQ's Game MVP with +20.36 total EPA on Passing plays. across 36 snaps. Their top snap (-4.18 EPA): (4:47) 13-B.Purdy pass short middle intended for 84-K.Bourne INTERCEPTED by 0-C.Bynum at IND 21. 0-C.Bynum to IND 29 for 8 yards (88-J.Tonges)..
Season records after this game
San Francisco 49ers
Entered 10-4 Now 11-4 W
Indianapolis Colts
Entered 8-6 Now 8-7 L
Fantasy · fantasyhq.co
