Quick answer
- Winner
- Buffalo Bills
- Final score
- Buffalo Bills 35–10 San Francisco 49ers
- Halftime
- San Francisco 49ers 3–21 Buffalo Bills at halftime
- FantasyHQ MVP
- Jonathan Allen
- Top passer
- Brock Purdy
- Biggest EPA play
- (11:57) 44-K.Juszczyk up the middle to BUF 1 for 3 yards (9-T.Rapp; 58-M.Milano). FUMBLES …
- Game date
- 2024-12-01
Game summary
The Buffalo Bills beat the San Francisco 49ers 35–10 on 2024-12-01. Jonathan Allen posted a game-high +11.40 total EPA in the passing.
The highest-scoring period was Q2 with 14 combined points.
Line score
Final score and points by quarter.
| Q1 | Q2 | Q3 | Q4 | — | T | |
|---|---|---|---|---|---|---|
| 3 | 0 | 7 | 0 | 0 | 10 | |
| 7 | 14 | 7 | 7 | 0 | 35 |
Stars of the game
Top performers by total expected points added (EPA).
- 1

Jonathan Allen · Buffalo Bills · Passing · +11.40 total EPA · 19 snaps · +0.60 EPA/play - 2

Jauan Jennings · San Francisco 49ers · Receiving · +6.16 total EPA · 5 snaps · +1.23 EPA/play - 3

Dawson Knox · Buffalo Bills · Receiving · +3.73 total EPA · 2 snaps · +1.86 EPA/play - 4

Ryan Davis · Buffalo Bills · Rushing · +3.28 total EPA · 12 snaps · +0.27 EPA/play - 5

Mack Hollins · Buffalo Bills · Receiving · +3.07 total EPA · 1 snaps · +3.07 EPA/play - 6

Christian McCaffrey · San Francisco 49ers · Rushing · +2.70 total EPA · 7 snaps · +0.39 EPA/play - 7

Jonathan Allen · Buffalo Bills · Rushing · +2.30 total EPA · 2 snaps · +1.15 EPA/play - 8

James Cook III · Buffalo Bills · Rushing · +2.10 total EPA · 14 snaps · +0.15 EPA/play
FantasyHQ Game MVP
Highest total EPA with the player's top snap and the game's biggest single play when different.

FantasyHQ Game MVP
Jonathan Allen — BUF · Passing
Jonathan Allen posted the highest total EPA (+11.40) in the game, the strongest overall impact for Buffalo Bills. Across 19 counted snaps, they averaged +0.60 EPA per play.
Jonathan Allen's top snap (+3.26 EPA): (6:50) (Shotgun) 17-J.Allen pass short left to 10-K.Shakir pushed ob at SF 7 for 18 yards (53-D.Winters).
Biggest single play (-8.84 EPA): Kyle Juszczyk — (11:57) 44-K.Juszczyk up the middle to BUF 1 for 3 yards (9-T.Rapp; 58-M.Milano). FUMBLES (9-T.Rapp), RECOVERED by BUF-47-C.Benford at BUF 5. 47-C.Benford pushed ob at BUF 48 for 43 yards (85-G.Kittle
Quarterback report card
Brock Purdy led all passers in efficiency for San Francisco 49ers, setting the tone in the passing game according to FantasyHQ analytics.

Brock Purdy (San Francisco 49ers) · 22 dropbacks · 50.0% completion · -8.1% CPOE · -0.29 EPA/play · -6.31 total EPA
Jonathan Allen (Buffalo Bills) · 19 dropbacks · 68.4% completion · +9.8% CPOE · +0.60 EPA/play · +11.40 total EPA
Team stats comparison
Side-by-side offensive and defensive efficiency.
| Stat | ||
|---|---|---|
| Offensive EPA/play | -0.255 | +0.145 |
| Offensive success rate | 35.4% | 50.7% |
| Pass EPA/play | -0.287 | +0.563 |
| Rush EPA/play | -0.152 | +0.220 |
| Defensive EPA/play | -0.145 | +0.255 |
| Defensive success rate | 49.3% | 64.6% |
Drive & efficiency notes
Buffalo Bills held the efficiency edge in offensive EPA per play (+0.14 vs -0.26), even if the scoreboard told a different story.
Season benchmark context (offensive EPA per play):
- San Francisco 49ers: -0.26 EPA/play (6th percentile vs. 2024 team-game averages)
- Buffalo Bills: +0.14 EPA/play (82nd percentile vs. 2024 team-game averages)
- Buffalo Bills: 10 drives, +10.30 total EPA, 5 scoring drives
- San Francisco 49ers: 10 drives, -16.60 total EPA, 2 scoring drives
Who scored touchdowns and field goals
Every touchdown and field goal from official play-by-play.
Touchdowns

Buffalo Bills — Ryan Davis 
Buffalo Bills — James Cook III 
Buffalo Bills — Mack Hollins (Jonathan Allen pass) 
Buffalo Bills — Amari Cooper (Jonathan Allen pass) 
San Francisco 49ers — Isaac Guerendo 
Buffalo Bills — Jonathan Allen
Field goals
San Francisco 49ers — Jaylen Moody
Quarter by quarter
Quarter-by-quarter recap from live scoring plays.
The opening quarter: Buffalo Bills won the period 7–3. San Francisco 49ers connected on a field goal from the BUF 15 (Q1 7:44) — (7:44) 4-J.Moody 33 yard field goal is GOOD, Center-46-T.Pepper, Holder-40-P.O'Donnell.; Buffalo Bills found the end zone from the SF 5 (Q1 0:08) — (:08) 70-A.Anderson reported in as eligible. 22-R.Davis right end for 5 yards, TOUCHDOWN.; Buffalo Bills added 1 points from the SF 15 (Q1 0:03) — 2-T.Bass extra point is GOOD, Center-69-R.Ferguson, Holder-8-S.Martin..
The second quarter: Buffalo Bills won the period 14–0. Buffalo Bills found the end zone from the SF 65 (Q2 8:48) — (8:48) 70-A.Anderson reported in as eligible. 4-J.Cook right tackle for 65 yards, TOUCHDOWN.; Buffalo Bills added 1 points from the SF 15 (Q2 8:38) — 2-T.Bass extra point is GOOD, Center-69-R.Ferguson, Holder-8-S.Martin.; Buffalo Bills found the end zone from the SF 7 (Q2 0:47) — (:47) (Shotgun) 17-J.Allen pass short right to 13-M.Hollins for 7 yards, TOUCHDOWN.; Buffalo Bills added 1 points from the SF 15 (Q2 0:41) — 2-T.Bass extra point is GOOD, Center-69-R.Ferguson, Holder-8-S.Martin..
The third quarter: The quarter finished even at 7–7. Buffalo Bills found the end zone from the SF 7 (Q3 6:05); Buffalo Bills added 1 points from the SF 15 (Q3 5:58) — 2-T.Bass extra point is GOOD, Center-69-R.Ferguson, Holder-8-S.Martin.; San Francisco 49ers found the end zone from the BUF 15 (Q3 3:00) — (3:00) (Shotgun) 31-I.Guerendo left end for 15 yards, TOUCHDOWN.; San Francisco 49ers added 1 points from the BUF 15 (Q3 2:54) — 4-J.Moody extra point is GOOD, Center-46-T.Pepper, Holder-40-P.O'Donnell..
The fourth quarter: Buffalo Bills won the period 7–0. Buffalo Bills found the end zone from the SF 8 (Q4 12:39) — (12:39) (Shotgun) 17-J.Allen scrambles right tackle for 8 yards, TOUCHDOWN.; Buffalo Bills added 1 points from the SF 15 (Q4 12:31) — 2-T.Bass extra point is GOOD, Center-69-R.Ferguson, Holder-8-S.Martin..
Turning points
Plays that moved win probability the most.
- Buffalo Bills (Q2 8:48) — (8:48) 70-A.Anderson reported in as eligible. 4-J.Cook right tackle for 65 yards, TOUCHDOWN.
- San Francisco 49ers (Q2 8:52) — (8:52) 4-J.Moody 45 yard field goal is No Good, Wide Left, Center-46-T.Pepper, Holder-40-P.O'Donnell.
- San Francisco 49ers (Q2 12:58) — (12:58) 23-C.McCaffrey left guard to BUF 30 for 18 yards (9-T.Rapp).
- Buffalo Bills (Q1 6:50) — (6:50) (Shotgun) 17-J.Allen pass incomplete short middle to 10-K.Shakir. PENALTY on SF-7-C.Ward, Illegal Contact, 5 yards, enforced at BUF 31 - No Play.
- San Francisco 49ers (Q2 11:23) — (11:23) 23-C.McCaffrey right end to BUF 34 for -5 yards (50-G.Rousseau). SF-23-C.McCaffrey was injured during the play.
Impact plays
Highest EPA snaps that flipped field position.
- San Francisco 49ers (Q3 11:57) — (11:57) 44-K.Juszczyk up the middle to BUF 1 for 3 yards (9-T.Rapp; 58-M.Milano). FUMBLES (9-T.Rapp), RECOVERED by BUF-47-C.Benford at BUF 5. 47-C.Benford pushed ob at BUF 48 for 43 yards (85-G.Kittle
- Buffalo Bills (Q2 8:48) — (8:48) 70-A.Anderson reported in as eligible. 4-J.Cook right tackle for 65 yards, TOUCHDOWN.
- San Francisco 49ers (Q4 12:31) — 2-T.Bass kicks 63 yards from BUF 35 to SF 2. 1-D.Samuel to SF 30 for 28 yards (24-C.Bishop; 85-Q.Morris). FUMBLES (24-C.Bishop), RECOVERED by BUF-89-J.Virgil at SF 31.
- San Francisco 49ers (Q3 4:22) — (4:22) (Shotgun) 13-B.Purdy pass short right to 15-J.Jennings to BUF 17 for 26 yards (7-Ta.Johnson, 43-T.Bernard).
Every scoring play
Chronological scoring with play-by-play context.
San Francisco 49ers FG (+3) — Q1 7:44 · BUF 15 · Score 3-0
(7:44) 4-J.Moody 33 yard field goal is GOOD, Center-46-T.Pepper, Holder-40-P.O'Donnell.
Buffalo Bills TD (+6) — Q1 0:08 · SF 5 · Score 3-6
(:08) 70-A.Anderson reported in as eligible. 22-R.Davis right end for 5 yards, TOUCHDOWN.
Buffalo Bills XP (+1) — Q1 0:03 · SF 15 · Score 3-7
2-T.Bass extra point is GOOD, Center-69-R.Ferguson, Holder-8-S.Martin.
Buffalo Bills TD (+6) — Q2 8:48 · SF 65 · Score 3-13
(8:48) 70-A.Anderson reported in as eligible. 4-J.Cook right tackle for 65 yards, TOUCHDOWN.
Buffalo Bills XP (+1) — Q2 8:38 · SF 15 · Score 3-14
2-T.Bass extra point is GOOD, Center-69-R.Ferguson, Holder-8-S.Martin.
Buffalo Bills TD (+6) — Q2 0:47 · SF 7 · Score 3-20
(:47) (Shotgun) 17-J.Allen pass short right to 13-M.Hollins for 7 yards, TOUCHDOWN.
Buffalo Bills XP (+1) — Q2 0:41 · SF 15 · Score 3-21
2-T.Bass extra point is GOOD, Center-69-R.Ferguson, Holder-8-S.Martin.
Buffalo Bills TD (+6) — Q3 6:05 · SF 7 · Score 3-27
(6:05) 70-A.Anderson reported in as eligible. 17-J.Allen pass short left to 18-A.Cooper to SF 9 for -2 yards. Lateral to 17-J.Allen for 9 yards, TOUCHDOWN.
Buffalo Bills XP (+1) — Q3 5:58 · SF 15 · Score 3-28
2-T.Bass extra point is GOOD, Center-69-R.Ferguson, Holder-8-S.Martin.
San Francisco 49ers TD (+6) — Q3 3:00 · BUF 15 · Score 9-28
(3:00) (Shotgun) 31-I.Guerendo left end for 15 yards, TOUCHDOWN.
San Francisco 49ers XP (+1) — Q3 2:54 · BUF 15 · Score 10-28
4-J.Moody extra point is GOOD, Center-46-T.Pepper, Holder-40-P.O'Donnell.
Buffalo Bills TD (+6) — Q4 12:39 · SF 8 · Score 10-34
(12:39) (Shotgun) 17-J.Allen scrambles right tackle for 8 yards, TOUCHDOWN.
Buffalo Bills XP (+1) — Q4 12:31 · SF 15 · Score 10-35
2-T.Bass extra point is GOOD, Center-69-R.Ferguson, Holder-8-S.Martin.
Key takeaways
What to remember for fantasy research and follow-up box score digging.
- Buffalo Bills earned the result — use the box score for snap-level context.
- Jonathan Allen (Buffalo Bills) led total EPA — start here for highlight and prop research.
- Brock Purdy (SF) finished below expected efficiency despite volume.
- Jonathan Allen (BUF) finished above expected through the air (positive CPOE).
Frequently asked questions
Who won San Francisco 49ers vs Buffalo Bills on 2024-12-01?
The Buffalo Bills beat the San Francisco 49ers 35-10 in Week 13, 2024.
What was the score by quarter in San Francisco 49ers vs Buffalo Bills?
Q1: San Francisco 49ers 3, Buffalo Bills 7; Q2: San Francisco 49ers 0, Buffalo Bills 14; Q3: San Francisco 49ers 7, Buffalo Bills 7; Q4: San Francisco 49ers 0, Buffalo Bills 7; Final: San Francisco 49ers 10, Buffalo Bills 35.
Who scored touchdowns and field goals in San Francisco 49ers vs Buffalo Bills?
Buffalo Bills touchdown — R. Davis (Q1 0:08) Buffalo Bills touchdown — J. Cook (Q2 8:48) Buffalo Bills touchdown — M. Hollins (J. Allen pass) (Q2 0:47) Buffalo Bills touchdown — A. Cooper (J. Allen pass) (Q3 6:05) San Francisco 49ers touchdown — I. Guerendo (Q3 3:00) Buffalo Bills touchdown — J. Allen (Q4 12:39) San Francisco 49ers field goal — J. Moody (Q1 7:44, 3 pts) Extra points followed each touchdown unless noted in the play-by-play.
How did the quarterbacks play in San Francisco 49ers vs Buffalo Bills?
Brock Purdy (San Francisco 49ers), 50.0% completion, -8.1% CPOE, -0.29 EPA per dropback, -6.31 total passing EPA. Jonathan Allen (Buffalo Bills), 68.4% completion, +9.8% CPOE, +0.60 EPA per dropback, +11.40 total passing EPA.
Who was FantasyHQ's player of the game in San Francisco 49ers vs Buffalo Bills?
Jonathan Allen (Buffalo Bills) was FantasyHQ's Game MVP with +11.40 total EPA on Passing plays. across 19 snaps. Their top snap (+3.26 EPA): (6:50) (Shotgun) 17-J.Allen pass short left to 10-K.Shakir pushed ob at SF 7 for 18 yards (53-D.Winters)..
Season records after this game
San Francisco 49ers
Entered 5-6 Now 5-7 L
Buffalo Bills
Entered 9-2 Now 10-2 W