49ers 10–17 Cardinals: Score, Stats & Recap | Week 5, 2021

Q: How did the quarterbacks play in San Francisco 49ers vs Arizona Cardinals?

T. Lance (San Francisco 49ers), 39.5% completion, -10.7% CPOE, -0.08 EPA per dropback, -2.97 total passing EPA. K. Murray (Arizona Cardinals), 64.7% completion, +10.8% CPOE, +0.01 EPA per dropback, +0.46 total passing EPA.

Q: Who was FantasyHQ's player of the game in San Francisco 49ers vs Arizona Cardinals?

D. Hopkins (Arizona Cardinals) was FantasyHQ's Game MVP with +6.89 total EPA on Receiving plays. across 9 snaps. Their top snap (+2.77 EPA): (10:47) (No Huddle, Shotgun) 1-K.Murray pass deep left to 10-D.Hopkins ran ob at ARI 27 for 23 yards. Penalty on SF-26-J.Norman, Defensive Pass Interference, declined..

Quick answer

Winner: Arizona Cardinals
Final score: Arizona Cardinals 17–10 San Francisco 49ers
Halftime: San Francisco 49ers 0–10 Arizona Cardinals at halftime
FantasyHQ MVP: Dustin Hopkins
Top passer: Trey Lance
Biggest EPA play: (8:45) (No Huddle, Shotgun) 1-K.Murray pass short right to 2-C.Edmonds to SF 47 for 2 yard…
Game date: 2021-10-10

Game summary

The Arizona Cardinals beat the San Francisco 49ers 17–10 on 2021-10-10. Dustin Hopkins posted a game-high +6.89 total EPA in the receiving.

The highest-scoring period was Q4 with 10 combined points.

Line score

Final score and points by quarter.

	Q1	Q2	Q3	Q4	—	T
San Francisco 49ers	0	0	7	3	0	10
Arizona Cardinals	7	3	0	7	0	17

Scoring Map

Each pin marks where a score occurred on the field — yard line from play-by-play.

SFSan Francisco 49ers

SF 1

+1SF 15

+3SF 3

ARI 13

+1ARI 15

SF 9

+1SF 15

+3ARI 29

ARIArizona Cardinals

FantasyHQ Analytics

Scoring timeline

8 scores

Chronological scoring plays — scroll to follow the game.

ARIArizona Cardinals
Q1 9:06TD
James Conner
Points+6
Yard line
SF 1
Score
0-6
(9:06) 6-J.Conner left end for 1 yard, TOUCHDOWN.
ARIArizona Cardinals
Q1 9:02XP
Matt Prater
Points+1
Yard line
SF 15
Score
0-7
5-M.Prater extra point is GOOD, Center-46-A.Brewer, Holder-14-A.Lee.
ARIArizona Cardinals
Q2 5:31FG
Matt Prater
Points+3
Yard line
SF 3
Score
0-10
(5:31) 5-M.Prater 21 yard field goal is GOOD, Center-46-A.Brewer, Holder-14-A.Lee.
SFSan Francisco 49ers
Q3 1:49TD
Deebo Samuel Sr.
Points+6
Yard line
ARI 13
Score
6-10
(1:49) (Shotgun) 19-D.Samuel left end for 13 yards, TOUCHDOWN.
SFSan Francisco 49ers
Q3 1:42XP
Joey Slye
Points+1
Yard line
ARI 15
Score
7-10
14-J.Slye extra point is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky.
ARIArizona Cardinals
Q4 5:19TD
Dustin Hopkins
Points+6
Yard line
SF 9
Score
7-16
(5:19) (Shotgun) 1-K.Murray pass short left to 10-D.Hopkins for 9 yards, TOUCHDOWN.
ARIArizona Cardinals
Q4 5:13XP
Matt Prater
Points+1
Yard line
SF 15
Score
7-17
5-M.Prater extra point is GOOD, Center-46-A.Brewer, Holder-14-A.Lee.
SFSan Francisco 49ers
Q4 4:17FG
Joey Slye
Points+3
Yard line
ARI 29
Score
10-17
(4:17) 14-J.Slye 47 yard field goal is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky.

Stars of the game

Top performers by total expected points added (EPA).

1Dustin Hopkins · Arizona Cardinals · Receiving · +6.89 total EPA · 9 snaps · +0.77 EPA/play
2M. Sanu · San Francisco 49ers · Receiving · +3.41 total EPA · 3 snaps · +1.14 EPA/play
3Brandon Aiyuk · San Francisco 49ers · Receiving · +2.61 total EPA · 4 snaps · +0.65 EPA/play
4Rondale Moore · Arizona Cardinals · Rushing · +2.58 total EPA · 3 snaps · +0.86 EPA/play
5Rondale Moore · Arizona Cardinals · Receiving · +2.52 total EPA · 6 snaps · +0.42 EPA/play
6Deebo Samuel Sr. · San Francisco 49ers · Rushing · +2.43 total EPA · 1 snaps · +2.43 EPA/play
7Kyle Juszczyk · San Francisco 49ers · Receiving · +1.97 total EPA · 4 snaps · +0.49 EPA/play
8Christian Kirk · Arizona Cardinals · Receiving · +1.70 total EPA · 5 snaps · +0.34 EPA/play

FantasyHQ Game MVP

Highest total EPA with the player's top snap and the game's biggest single play when different.

FantasyHQ Game MVP

Dustin Hopkins — ARI · Receiving

Dustin Hopkins posted the highest total EPA (+6.89) in the game, the strongest overall impact for Arizona Cardinals. Across 9 counted snaps, they averaged +0.77 EPA per play.

Dustin Hopkins's top snap (+2.77 EPA): (10:47) (No Huddle, Shotgun) 1-K.Murray pass deep left to 10-D.Hopkins ran ob at ARI 27 for 23 yards. Penalty on SF-26-J.Norman, Defensive Pass Interference, declined.

Biggest single play (-4.93 EPA): Kenneth Murray, Jr. — (8:45) (No Huddle, Shotgun) 1-K.Murray pass short right to 2-C.Edmonds to SF 47 for 2 yards (27-D.Johnson). San Francisco challenged the runner was down by contact ruling, and the play was REVERSED. (

Quarterback report card

Trey Lance led all passers in efficiency for San Francisco 49ers, setting the tone in the passing game according to FantasyHQ analytics.

Trey Lance (San Francisco 49ers) · 38 dropbacks · 39.5% completion · -10.7% CPOE · -0.08 EPA/play · -2.97 total EPA
Kenneth Murray, Jr. (Arizona Cardinals) · 34 dropbacks · 64.7% completion · +10.8% CPOE · +0.01 EPA/play · +0.46 total EPA

Team stats comparison

Side-by-side offensive and defensive efficiency.

Stat	San Francisco 49ers	Arizona Cardinals
Offensive EPA/play	-0.152	-0.061
Offensive success rate	36.8%	43.2%
Pass EPA/play	-0.078	+0.013
Rush EPA/play	-0.367	-0.025
Defensive EPA/play	+0.061	+0.152
Defensive success rate	56.8%	63.2%

Drive & efficiency notes

Arizona Cardinals held the efficiency edge in offensive EPA per play (-0.06 vs -0.15), even if the scoreboard told a different story.

Season benchmark context (offensive EPA per play):

San Francisco 49ers: -0.15 EPA/play (18th percentile vs. 2021 team-game averages)
Arizona Cardinals: -0.06 EPA/play (37th percentile vs. 2021 team-game averages)

Arizona Cardinals: 10 drives, -4.54 total EPA, 3 scoring drives
San Francisco 49ers: 9 drives, -11.57 total EPA, 2 scoring drives

Who scored touchdowns and field goals

Every touchdown and field goal from official play-by-play.

Touchdowns

Arizona Cardinals — James Conner (Q1 9:06)
San Francisco 49ers — Deebo Samuel Sr. (Q3 1:49)
Arizona Cardinals — Dustin Hopkins (Kenneth Murray, Jr. pass) (Q4 5:19)

Field goals

Arizona Cardinals — Matt Prater (Q2 5:31)
San Francisco 49ers — Joey Slye (Q4 4:17)

Quarter by quarter

Quarter-by-quarter recap from live scoring plays.

The opening quarter: Arizona Cardinals won the period 7–0. Arizona Cardinals found the end zone from the SF 1 (Q1 9:06) — (9:06) 6-J.Conner left end for 1 yard, TOUCHDOWN.; Arizona Cardinals added 1 points from the SF 15 (Q1 9:02) — 5-M.Prater extra point is GOOD, Center-46-A.Brewer, Holder-14-A.Lee..

The second quarter: Arizona Cardinals won the period 3–0. Arizona Cardinals connected on a field goal from the SF 3 (Q2 5:31) — (5:31) 5-M.Prater 21 yard field goal is GOOD, Center-46-A.Brewer, Holder-14-A.Lee..

The third quarter: San Francisco 49ers won the period 7–0. San Francisco 49ers found the end zone from the ARI 13 (Q3 1:49) — (1:49) (Shotgun) 19-D.Samuel left end for 13 yards, TOUCHDOWN.; San Francisco 49ers added 1 points from the ARI 15 (Q3 1:42) — 14-J.Slye extra point is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky..

The fourth quarter: Arizona Cardinals won the period 7–3. Arizona Cardinals found the end zone from the SF 9 (Q4 5:19) — (5:19) (Shotgun) 1-K.Murray pass short left to 10-D.Hopkins for 9 yards, TOUCHDOWN.; Arizona Cardinals added 1 points from the SF 15 (Q4 5:13) — 5-M.Prater extra point is GOOD, Center-46-A.Brewer, Holder-14-A.Lee.; San Francisco 49ers connected on a field goal from the ARI 29 (Q4 4:17) — (4:17) 14-J.Slye 47 yard field goal is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky..

Turning points

Plays that moved win probability the most.

Arizona Cardinals (Q4 8:45) — (8:45) (No Huddle, Shotgun) 1-K.Murray pass short right to 2-C.Edmonds to SF 47 for 2 yards (27-D.Johnson). San Francisco challenged the runner was down by contact ruling, and the play was REVERSED. ( [WPA -16.8% · EPA -4.93]
San Francisco 49ers (Q4 9:23) — (9:23) Direct snap to 44-K.Juszczyk. 44-K.Juszczyk up the middle to ARI 48 for no gain (94-Z.Allen). [WPA -14.1% · EPA -3.65]
San Francisco 49ers (Q4 7:53) — (7:53) (Shotgun) 5-T.Lance pass incomplete short middle to 19-D.Samuel (99-J.Watt). [WPA -14.0% · EPA -2.85]
San Francisco 49ers (Q1 12:57) — (12:57) 5-T.Lance pass deep middle intended for 17-T.Benjamin INTERCEPTED by 3-B.Baker at ARI 17. 3-B.Baker to ARI 34 for 17 yards (82-R.Dwelley). [WPA -9.6% · EPA -4.60]
San Francisco 49ers (Q4 12:37) — (12:37) (Shotgun) 5-T.Lance scrambles up the middle ran ob at SF 38 for 15 yards (33-A.Hamilton). PENALTY on ARI-33-A.Hamilton, Illegal Contact, 5 yards, enforced at SF 38. [WPA +8.8% · EPA +2.63]

Impact plays

Highest EPA snaps that flipped field position.

Arizona Cardinals (Q4 8:45) — (8:45) (No Huddle, Shotgun) 1-K.Murray pass short right to 2-C.Edmonds to SF 47 for 2 yards (27-D.Johnson). San Francisco challenged the runner was down by contact ruling, and the play was REVERSED. ( [WPA -16.8% · EPA -4.93]
San Francisco 49ers (Q1 12:57) — (12:57) 5-T.Lance pass deep middle intended for 17-T.Benjamin INTERCEPTED by 3-B.Baker at ARI 17. 3-B.Baker to ARI 34 for 17 yards (82-R.Dwelley). [WPA -9.6% · EPA -4.60]
San Francisco 49ers (Q2 11:34) — (11:34) 5-T.Lance sacked at ARI 1 for 0 yards (sack split by 51-T.Vallejo and 9-I.Simmons). ARI-9-I.Simmons was injured during the play. [WPA -6.0% · EPA -4.35]
San Francisco 49ers (Q3 4:33) — (4:33) (Shotgun) 5-T.Lance pass short right to 11-B.Aiyuk ran ob at ARI 48 for 26 yards (3-B.Baker). PENALTY on ARI-55-C.Jones, Lowering the Head to Initiate Contact, 15 yards, enforced at ARI 48. [WPA +8.3% · EPA +3.74]

Every scoring play

Chronological scoring with play-by-play context.

Arizona Cardinals TD (+6) — Q1 9:06 · SF 1 · Score 0-6
(9:06) 6-J.Conner left end for 1 yard, TOUCHDOWN.
Arizona Cardinals XP (+1) — Q1 9:02 · SF 15 · Score 0-7
5-M.Prater extra point is GOOD, Center-46-A.Brewer, Holder-14-A.Lee.
Arizona Cardinals FG (+3) — Q2 5:31 · SF 3 · Score 0-10
(5:31) 5-M.Prater 21 yard field goal is GOOD, Center-46-A.Brewer, Holder-14-A.Lee.
San Francisco 49ers TD (+6) — Q3 1:49 · ARI 13 · Score 6-10
(1:49) (Shotgun) 19-D.Samuel left end for 13 yards, TOUCHDOWN.
San Francisco 49ers XP (+1) — Q3 1:42 · ARI 15 · Score 7-10
14-J.Slye extra point is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky.
Arizona Cardinals TD (+6) — Q4 5:19 · SF 9 · Score 7-16
(5:19) (Shotgun) 1-K.Murray pass short left to 10-D.Hopkins for 9 yards, TOUCHDOWN.
Arizona Cardinals XP (+1) — Q4 5:13 · SF 15 · Score 7-17
5-M.Prater extra point is GOOD, Center-46-A.Brewer, Holder-14-A.Lee.
San Francisco 49ers FG (+3) — Q4 4:17 · ARI 29 · Score 10-17
(4:17) 14-J.Slye 47 yard field goal is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky.

Key takeaways

What to remember for fantasy research and follow-up box score digging.

Arizona Cardinals earned the result — use the box score for snap-level context.
One-score margin — verify garbage-time stats before drawing fantasy conclusions.
Dustin Hopkins (Arizona Cardinals) led total EPA — start here for highlight and prop research.
Trey Lance (SF) finished below expected efficiency despite volume.

Frequently asked questions

Who won San Francisco 49ers vs Arizona Cardinals on 2021-10-10?

The Arizona Cardinals beat the San Francisco 49ers 17-10 in Week 5, 2021.

What was the score by quarter in San Francisco 49ers vs Arizona Cardinals?

Q1: San Francisco 49ers 0, Arizona Cardinals 7; Q2: San Francisco 49ers 0, Arizona Cardinals 3; Q3: San Francisco 49ers 7, Arizona Cardinals 0; Q4: San Francisco 49ers 3, Arizona Cardinals 7; Final: San Francisco 49ers 10, Arizona Cardinals 17.

Who scored touchdowns and field goals in San Francisco 49ers vs Arizona Cardinals?

Arizona Cardinals touchdown — J. Conner (Q1 9:06) San Francisco 49ers touchdown — D. Samuel (Q3 1:49) Arizona Cardinals touchdown — D. Hopkins (K. Murray pass) (Q4 5:19) Arizona Cardinals field goal — M. Prater (Q2 5:31, 3 pts) San Francisco 49ers field goal — J. Slye (Q4 4:17, 3 pts) Extra points followed each touchdown unless noted in the play-by-play.

How did the quarterbacks play in San Francisco 49ers vs Arizona Cardinals?

Trey Lance (San Francisco 49ers), 39.5% completion, -10.7% CPOE, -0.08 EPA per dropback, -2.97 total passing EPA. Kenneth Murray, Jr. (Arizona Cardinals), 64.7% completion, +10.8% CPOE, +0.01 EPA per dropback, +0.46 total passing EPA.

Who was FantasyHQ's player of the game in San Francisco 49ers vs Arizona Cardinals?

Dustin Hopkins (Arizona Cardinals) was FantasyHQ's Game MVP with +6.89 total EPA on Receiving plays. across 9 snaps. Their top snap (+2.77 EPA): (10:47) (No Huddle, Shotgun) 1-K.Murray pass deep left to 10-D.Hopkins ran ob at ARI 27 for 23 yards. Penalty on SF-26-J.Norman, Defensive Pass Interference, declined..

Was San Francisco 49ers vs Arizona Cardinals a close game?

Yes — the margin was 7 points. Arizona Cardinals won 17-10 in a game that stayed within one score into the fourth quarter.

Season records after this game

San Francisco 49ers

Entered 2-2 Now 2-3 L

Arizona Cardinals

Entered 4-0 Now 5-0 W

San Francisco 49ers vs. Arizona Cardinals: 2021 Week 5 Recap

Top fantasy performers · 49ers

Top fantasy performers · Cardinals

Quick answer

Game summary