Quick answer
- Winner
- Indianapolis Colts
- Final score
- Indianapolis Colts 22–16 Arizona Cardinals
- Halftime
- Indianapolis Colts 12–6 Arizona Cardinals at halftime
- FantasyHQ MVP
- Carson Wentz
- Top passer
- Kenneth Murray, Jr.
- Biggest EPA play
- (4:28) (No Huddle, Shotgun) 1-K.Murray left tackle to IND 2 for 57 yards (30-G.Odum).
- Game date
- 2021-12-25
Game summary
The Indianapolis Colts beat the Arizona Cardinals 22–16 on 2021-12-25. Carson Wentz posted a game-high +9.50 total EPA in the passing.
The highest-scoring period was Q1 with 13 combined points.
Line score
Final score and points by quarter.
| Q1 | Q2 | Q3 | Q4 | — | T | |
|---|---|---|---|---|---|---|
| 7 | 5 | 3 | 7 | 0 | 22 | |
| 6 | 0 | 7 | 3 | 0 | 16 |
Stars of the game
Top performers by total expected points added (EPA).
- 1

Carson Wentz · Indianapolis Colts · Passing · +9.50 total EPA · 37 snaps · +0.26 EPA/play - 2
T. Hilton · Indianapolis Colts · Receiving · +4.20 total EPA · 5 snaps · +0.84 EPA/play - 3
Dezmon Patmon · Indianapolis Colts · Receiving · +3.24 total EPA · 1 snaps · +3.24 EPA/play - 4

Kenneth Murray, Jr. · Arizona Cardinals · Rushing · +2.54 total EPA · 4 snaps · +0.64 EPA/play - 5

Chris Edmonds · Arizona Cardinals · Receiving · +2.47 total EPA · 9 snaps · +0.27 EPA/play - 6

Mo Alie-Cox · Indianapolis Colts · Receiving · +2.35 total EPA · 4 snaps · +0.59 EPA/play - 7

Jonathan Ward · Arizona Cardinals · Rushing · +2.31 total EPA · 1 snaps · +2.31 EPA/play - 8

Ashton Dulin · Indianapolis Colts · Receiving · +1.97 total EPA · 2 snaps · +0.98 EPA/play
FantasyHQ Game MVP
Highest total EPA with the player's top snap and the game's biggest single play when different.

FantasyHQ Game MVP
Carson Wentz — IND · Passing
Carson Wentz posted the highest total EPA (+9.50) in the game, the strongest overall impact for Indianapolis Colts. Across 37 counted snaps, they averaged +0.26 EPA per play.
Carson Wentz's top snap (+3.52 EPA): (4:02) (Shotgun) 2-C.Wentz pass short left to 81-M.Alie-Cox to ARI 32 for 37 yards (3-B.Baker).
Biggest single play (+3.97 EPA): Kenneth Murray, Jr. — (4:28) (No Huddle, Shotgun) 1-K.Murray left tackle to IND 2 for 57 yards (30-G.Odum).
Quarterback report card
Kenneth Murray, Jr. led all passers in efficiency for Arizona Cardinals, setting the tone in the passing game according to FantasyHQ analytics.

Kenneth Murray, Jr. (Arizona Cardinals) · 44 dropbacks · 61.4% completion · -1.4% CPOE · -0.07 EPA/play · -3.04 total EPA
Carson Wentz (Indianapolis Colts) · 37 dropbacks · 48.6% completion · -2.8% CPOE · +0.26 EPA/play · +9.50 total EPA
Team stats comparison
Side-by-side offensive and defensive efficiency.
| Stat | ||
|---|---|---|
| Offensive EPA/play | -0.026 | -0.117 |
| Offensive success rate | 37.9% | 41.2% |
| Pass EPA/play | +0.257 | -0.069 |
| Rush EPA/play | -0.182 | +0.273 |
| Defensive EPA/play | +0.117 | +0.026 |
| Defensive success rate | 58.8% | 62.1% |
Drive & efficiency notes
Despite the final score, Indianapolis Colts generated the better offensive EPA per play (-0.03 vs -0.12), suggesting they moved the ball more efficiently.
Season benchmark context (offensive EPA per play):
- Indianapolis Colts: -0.03 EPA/play (44th percentile vs. 2021 team-game averages)
- Arizona Cardinals: -0.12 EPA/play (25th percentile vs. 2021 team-game averages)
- Arizona Cardinals: 10 drives, -9.34 total EPA, 4 scoring drives
- Indianapolis Colts: 10 drives, -2.27 total EPA, 4 scoring drives
Who scored touchdowns and field goals
Every touchdown and field goal from official play-by-play.
Touchdowns
Indianapolis Colts — T. Hilton (Carson Wentz pass) 
Arizona Cardinals — Chris Edmonds
Arizona Cardinals — Antoine Wesley (Kenneth Murray, Jr. pass)
Indianapolis Colts — Dezmon Patmon (Carson Wentz pass)
Field goals

Indianapolis Colts — Michael Badgley 
Indianapolis Colts — Michael Badgley
Arizona Cardinals — Matt Prater
Quarter by quarter
Quarter-by-quarter recap from live scoring plays.
The opening quarter: Indianapolis Colts won the period 7–6. Indianapolis Colts found the end zone from the ARI 1 (Q1 6:16) — (6:16) (Shotgun) 2-C.Wentz pass short left to 13-T.Hilton for 1 yard, TOUCHDOWN.; Indianapolis Colts added 1 points from the ARI 15 (Q1 6:11) — 6-M.Badgley extra point is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.; Arizona Cardinals found the end zone from the IND 2 (Q1 3:06) — (3:06) 2-C.Edmonds up the middle for 2 yards, TOUCHDOWN..
The second quarter: Indianapolis Colts won the period 5–0. Indianapolis Colts registered a safety from the IND 89 (Q2 4:25); Indianapolis Colts connected on a field goal from the ARI 23 (Q2 0:05) — (:05) 6-M.Badgley 41 yard field goal is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez..
The third quarter: Arizona Cardinals won the period 7–3. Arizona Cardinals found the end zone from the IND 24 (Q3 10:58) — (10:58) (No Huddle, Shotgun) 1-K.Murray pass deep left to 85-A.Wesley for 24 yards, TOUCHDOWN.; Arizona Cardinals added 1 points from the IND 15 (Q3 10:53) — 5-M.Prater extra point is GOOD, Center-46-A.Brewer, Holder-16-R.Winslow.; Indianapolis Colts connected on a field goal from the ARI 19 (Q3 0:07) — (:07) 6-M.Badgley 37 yard field goal is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez..
The fourth quarter: Indianapolis Colts won the period 7–3. Indianapolis Colts found the end zone from the ARI 14 (Q4 6:45); Indianapolis Colts added 1 points from the ARI 7 (Q4 6:37) — 6-M.Badgley extra point is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.; Arizona Cardinals connected on a field goal from the IND 10 (Q4 0:46) — (:46) 5-M.Prater 28 yard field goal is GOOD, Center-46-A.Brewer, Holder-16-R.Winslow..
Turning points
Plays that moved win probability the most.
- Arizona Cardinals (Q4 11:12) — (11:12) 5-M.Prater 41 yard field goal is No Good, Hit Right Upright, Center-46-A.Brewer, Holder-16-R.Winslow.
- Arizona Cardinals (Q4 13:10) — (13:10) (Shotgun) 1-K.Murray pass deep right to 18-A.Green to IND 30 for 33 yards (27-X.Rhodes).
- Indianapolis Colts (Q4 8:51) — (8:51) (Shotgun) 2-C.Wentz pass deep right to 13-T.Hilton pushed ob at ARI 15 for 39 yards (3-B.Baker).
- Indianapolis Colts (Q3 4:02) — (4:02) (Shotgun) 2-C.Wentz pass short left to 81-M.Alie-Cox to ARI 32 for 37 yards (3-B.Baker).
- Indianapolis Colts (Q2 14:14) — (14:14) 6-M.Badgley 53 yard field goal is No Good, Short, Center-46-L.Rhodes, Holder-8-R.Sanchez.
Impact plays
Highest EPA snaps that flipped field position.
- Arizona Cardinals (Q1 4:28) — (4:28) (No Huddle, Shotgun) 1-K.Murray left tackle to IND 2 for 57 yards (30-G.Odum).
- Indianapolis Colts (Q2 14:14) — (14:14) 6-M.Badgley 53 yard field goal is No Good, Short, Center-46-L.Rhodes, Holder-8-R.Sanchez.
- Arizona Cardinals (Q4 11:12) — (11:12) 5-M.Prater 41 yard field goal is No Good, Hit Right Upright, Center-46-A.Brewer, Holder-16-R.Winslow.
- Indianapolis Colts (Q3 4:02) — (4:02) (Shotgun) 2-C.Wentz pass short left to 81-M.Alie-Cox to ARI 32 for 37 yards (3-B.Baker).
Every scoring play
Chronological scoring with play-by-play context.
Indianapolis Colts TD (+6) — Q1 6:16 · ARI 1 · Score 6-0
(6:16) (Shotgun) 2-C.Wentz pass short left to 13-T.Hilton for 1 yard, TOUCHDOWN.
Indianapolis Colts XP (+1) — Q1 6:11 · ARI 15 · Score 7-0
6-M.Badgley extra point is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.
Arizona Cardinals TD (+6) — Q1 3:06 · IND 2 · Score 7-6
(3:06) 2-C.Edmonds up the middle for 2 yards, TOUCHDOWN.
Indianapolis Colts Safety (+2) — Q2 4:25 · IND 89 · Score 9-6
(4:25) (Shotgun) 1-K.Murray to ARI 6 for -5 yards. FUMBLES, and recovers at ARI -5. 1-K.Murray pass incomplete short right. PENALTY on ARI-1-K.Murray, Intentional Grounding, 11 yards, enforced in End
Indianapolis Colts FG (+3) — Q2 0:05 · ARI 23 · Score 12-6
(:05) 6-M.Badgley 41 yard field goal is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.
Arizona Cardinals TD (+6) — Q3 10:58 · IND 24 · Score 12-12
(10:58) (No Huddle, Shotgun) 1-K.Murray pass deep left to 85-A.Wesley for 24 yards, TOUCHDOWN.
Arizona Cardinals XP (+1) — Q3 10:53 · IND 15 · Score 12-13
5-M.Prater extra point is GOOD, Center-46-A.Brewer, Holder-16-R.Winslow.
Indianapolis Colts FG (+3) — Q3 0:07 · ARI 19 · Score 15-13
(:07) 6-M.Badgley 37 yard field goal is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.
Indianapolis Colts TD (+6) — Q4 6:45 · ARI 14 · Score 21-13
(6:45) (Shotgun) 2-C.Wentz pass short left to 10-D.Patmon for 14 yards, TOUCHDOWN. PENALTY on ARI-94-Z.Allen, Roughing the Passer, 8 yards, enforced between downs.
Indianapolis Colts XP (+1) — Q4 6:37 · ARI 7 · Score 22-13
6-M.Badgley extra point is GOOD, Center-46-L.Rhodes, Holder-8-R.Sanchez.
Arizona Cardinals FG (+3) — Q4 0:46 · IND 10 · Score 22-16
(:46) 5-M.Prater 28 yard field goal is GOOD, Center-46-A.Brewer, Holder-16-R.Winslow.
Key takeaways
What to remember for fantasy research and follow-up box score digging.
- Indianapolis Colts earned the result — use the box score for snap-level context.
- One-score margin — verify garbage-time stats before drawing fantasy conclusions.
- Carson Wentz (Indianapolis Colts) led total EPA — start here for highlight and prop research.
Frequently asked questions
Who won Indianapolis Colts vs Arizona Cardinals on 2021-12-25?
The Indianapolis Colts beat the Arizona Cardinals 22-16 in Week 16, 2021.
What was the score by quarter in Indianapolis Colts vs Arizona Cardinals?
Q1: Indianapolis Colts 7, Arizona Cardinals 6; Q2: Indianapolis Colts 5, Arizona Cardinals 0; Q3: Indianapolis Colts 3, Arizona Cardinals 7; Q4: Indianapolis Colts 7, Arizona Cardinals 3; Final: Indianapolis Colts 22, Arizona Cardinals 16.
Who scored touchdowns and field goals in Indianapolis Colts vs Arizona Cardinals?
Indianapolis Colts touchdown — T. Hilton (C. Wentz pass) (Q1 6:16) Arizona Cardinals touchdown — C. Edmonds (Q1 3:06) Arizona Cardinals touchdown — A. Wesley (K. Murray pass) (Q3 10:58) Indianapolis Colts touchdown — D. Patmon (C. Wentz pass) (Q4 6:45) Indianapolis Colts field goal — M. Badgley (Q2 0:05, 3 pts) Indianapolis Colts field goal — M. Badgley (Q3 0:07, 3 pts) Arizona Cardinals field goal — M. Prater (Q4 0:46, 3 pts) Extra points followed each touchdown unless noted in the play-by-play.
How did the quarterbacks play in Indianapolis Colts vs Arizona Cardinals?
Kenneth Murray, Jr. (Arizona Cardinals), 61.4% completion, -1.4% CPOE, -0.07 EPA per dropback, -3.04 total passing EPA. Carson Wentz (Indianapolis Colts), 48.6% completion, -2.8% CPOE, +0.26 EPA per dropback, +9.50 total passing EPA.
Who was FantasyHQ's player of the game in Indianapolis Colts vs Arizona Cardinals?
Carson Wentz (Indianapolis Colts) was FantasyHQ's Game MVP with +9.50 total EPA on Passing plays. across 37 snaps. Their top snap (+3.52 EPA): (4:02) (Shotgun) 2-C.Wentz pass short left to 81-M.Alie-Cox to ARI 32 for 37 yards (3-B.Baker)..
Was Indianapolis Colts vs Arizona Cardinals a close game?
Yes — the margin was 6 points. Indianapolis Colts won 22-16 in a game that stayed within one score into the fourth quarter.
Season records after this game
Indianapolis Colts
Entered 8-6 Now 9-6 W
Arizona Cardinals
Entered 10-4 Now 10-5 L