Eastern Kentucky Colonels 17–51 Louisville Cardinals: Final Score & Recap | Week 1, 2025

Quick answer

Louisville Cardinals defeated Eastern Kentucky Colonels 51–17 in Week 1, 2025. Final score: Eastern Kentucky Colonels 17, Louisville Cardinals 51.

Game summary

Louisville Cardinals dominated Eastern Kentucky Colonels 51–17 in Week 1 of the 2025 season.

Scoring: 9 touchdowns, 2 field goals across 11 plays.
Passing leader: Miller Moss (Louisville) — 290.0 pass yds, 1 TD, +0.14 EPA/play.
Rushing leader: Brayden Latham — 25.0 yds.
Receiving leader: Chris Bell — 5 rec, 58.0 yds.
EPA edge: Louisville (+0.140/play) vs Eastern Kentucky (-0.241/play).

Line score

Final score and points by quarter.

Team	Q1	Q2	Q3	Q4	Final
Eastern Kentucky Colonels	6	0	0	9	17
Louisville Cardinals	12	24	6	3	51

Scoring Map

Each pin marks a score on the field — TDs in the end zone, field goals near the kick line.

EKUEastern Kentucky Colonels

OPP EZ

+3

+3OPP 21

LOULouisville Cardinals

FantasyHQ CFB Analytics

Scoring timeline

11 scores

Chronological scoring plays — scroll to follow the game.

Louisville
Q1TD
IBIsaac Brown
Points+6
Yard line
OPP EZ
Score
0-6
Isaac Brown rushes 31 yards for a touchdown
Eastern Kentucky
Q1TD
Points+6
Yard line
OPP EZ
Score
6-6
Punt return touchdown
Louisville
Q1TD
MMMiller Moss
Points+6
Yard line
OPP EZ
Score
6-12
Miller Moss rushes 8 yards for a touchdown
Louisville
Q2TD
IBIsaac Brown
Points+6
Yard line
OPP EZ
Score
6-18
Isaac Brown rushes 68 yards for a touchdown
Louisville
Q2TD
DWDuke Watson
Points+6
Yard line
OPP EZ
Score
6-24
Miller Moss pass to Duke Watson for a touchdown (30 yards)
Louisville
Q2TD
KBKeyjuan Brown
Points+6
Yard line
OPP EZ
Score
6-30
Keyjuan Brown rushes 1 yard for a touchdown
Louisville
Q2TD
MMMiller Moss
Points+6
Yard line
OPP EZ
Score
6-36
Miller Moss — Interception returned for a touchdown
Louisville
Q3TD
KHKris Hughes
Points+6
Yard line
OPP EZ
Score
6-42
Brady Allen pass to Kris Hughes for a touchdown (31 yards)
Eastern Kentucky
Q4TD
BHBrady Hensley
Points+6
Yard line
OPP EZ
Score
12-42
Brady Hensley rushes 2 yards for a touchdown
Louisville
Q4FG
Points+3
Yard line
OPP 6
Score
12-45
Field goal good from 23 yards
Eastern Kentucky
Q4FG
Points+3
Yard line
OPP 21
Score
15-45
Field goal good from 38 yards

Stars of the game

Top passers, rushers, and receivers from cfbfastR play-by-play.

Passing

Miller Moss (Louisville) — 290.0 yds · 1 TD · +0.14 EPA/play +3.56 EPA
Deuce Adams (Louisville) — 21.0 yds · +0.37 EPA/play +0.75 EPA
Brady Allen (Louisville) — 89.0 yds · 1 TD · -0.38 EPA/play -3.41 EPA

Rushing

Brayden Latham (Eastern Kentucky) — 25.0 yds -0.23 EPA
Brady Hensley (Eastern Kentucky) — 24.0 yds · 1 TD -0.03 EPA
Myles Burkett (Eastern Kentucky) — 44.0 yds +0.67 EPA

Receiving

Chris Bell (Louisville) — 5 rec · 58.0 yds +0.49 EPA
Caullin Lacy (Louisville) — 4 rec · 62.0 yds +0.53 EPA
Kris Hughes (Louisville) — 3 rec · 50.0 yds +0.32 EPA

Quarterback report card

Attempts, efficiency, and EPA.

Player	Team	Att	Cmp%	Yds	TD	EPA/play	Total EPA
Miller Moss	Louisville	25	68.0%	290	1	+0.14	+3.56
Deuce Adams	Louisville	2	100.0%	21	0	+0.37	+0.75
Brady Allen	Louisville	9	66.7%	89	1	-0.38	-3.41
Myles Burkett	Eastern Kentucky	18	27.8%	47	0	-0.72	-12.99

Team EPA comparison

Stat	Eastern Kentucky	Louisville
Plays	53	66
EPA / play	-0.241	+0.140
Total EPA	-12.79	+9.22
Success rate	20.8%	59.1%
Pass EPA / play	-0.722	+0.025
Rush EPA / play	+0.006	+0.277
Yards	160	629

Drive chart

Key possessions and results.

Qtr	Offense	Plays	Yards	EPA	Result
Q1	Louisville	10	95	+8.55	Rush TD
Q1	Eastern Kentucky	3	-5	-4.65	Touchdown
Q1	Eastern Kentucky	3	-2	-2.60	Punt
Q1	Louisville	10	79	+5.35	Rush TD
Q1	Eastern Kentucky	6	9	-2.49	Punt
Q2	Louisville	3	75	+4.67	Rush TD
Q2	Eastern Kentucky	3	6	-1.05	Punt
Q2	Louisville	1	30	+2.41	Pass TD
Q2	Eastern Kentucky	3	5	-1.76	Punt
Q2	Louisville	10	67	+2.96	Rush TD
Q2	Eastern Kentucky	4	26	+0.56	Punt
Q2	Louisville	1	29	-8.11	Touchdown
Q2	Louisville	4	65	-2.24	Interception
Q2	Eastern Kentucky	1	-1	0.00	Ended
Q3	Eastern Kentucky	3	4	-2.34	Punt
Q3	Louisville	5	17	-1.92	Punt

Biggest EPA swings

Q2 · Louisville Cardinals · Miller Moss — Interception returned for a touchdown (-8.11 EPA)
Q3 · Louisville Cardinals · Brady Allen pass intercepted (-5.73 EPA)
Q1 · Eastern Kentucky Colonels · Punt return touchdown (-5.13 EPA)
Q2 · Louisville Cardinals · Isaac Brown rushes 68 yards for a touchdown (+5.03 EPA)
Q1 · Louisville Cardinals · Miller Moss pass to Antonio Meeks for 21 yards (3rd & 19) (+4.21 EPA)
Q3 · Eastern Kentucky Colonels · Myles Burkett rushes for 16 yards (3rd & 8) (+3.37 EPA)
Q1 · Louisville Cardinals · Miller Moss pass to Caullin Lacy for 32 yards (2nd & 10) (+3.16 EPA)
Q1 · Eastern Kentucky Colonels · Myles Burkett sacked for a loss of 9 yards (3rd & 6) (-3.0 EPA)

Key takeaways

Louisville Cardinals controlled the final (51–17) in Week 1.
Passing edge: Miller Moss (Louisville) — 290.0 yds, 1 TD.
EPA edge: Louisville at 0.14 EPA/play.
Full EPA, scoring map, and play-by-play live in CFB Analytics Box & Scores.

Frequently asked questions

What was the final score of Eastern Kentucky Colonels vs Louisville Cardinals?

Eastern Kentucky Colonels 17, Louisville Cardinals 51 in Week 1 of the 2025 college football season.

Who won Eastern Kentucky Colonels vs Louisville Cardinals?

Louisville Cardinals won with a final score of 17–51.

Where can I find the Eastern Kentucky Colonels vs Louisville Cardinals box score?

See EPA, scoring timeline, and full play-by-play on FantasyHQ CFB Analytics: /cfb-analytics?game=401754519.

Who led Eastern Kentucky Colonels vs Louisville Cardinals in passing?

Miller Moss (Louisville) led passers with 290.0 yards and 1 touchdowns.

Full analytics box score

Explore every snap, drive chart, and the interactive scoring map for Eastern Kentucky Colonels at Louisville Cardinals in FantasyHQ CFB Analytics Box & Scores.