Talanoa Hufanga was drafted No. 180 overall by the San Francisco 49ers in the 2021 NFL Draft out of USC. 66 regular-season games · 3 seasons as a starter · 29 career approximate value
2021 NFL Draft · Rd 5, Pick 36 · #180 overall
Talanoa Hufanga USC Draft
Talanoa Hufanga was drafted No. 180 overall by the San Francisco 49ers in the 2021 NFL Draft out of USC. 66 regular-season games · 3 seasons as a starter · 29 career approximate value
1× All-Pro 1× Pro Bowl
- Overall pick
- #180
- Round
- 5
- Draft class
- 2021
- NFL games
- 66
- Years as starter
- 3
- Career AV
- 2966th at USC
- Pro Bowls
- 1
- All-Pro
- 1
The pick
How Talanoa Hufanga came off the board in 2021.
- Position
- Safety S
- College
-
USC
Pac-12 at the draft
- Measurables
- 6'0" · 199 lbs
- Hometown
- Corvallis, OR
- Pre-draft board
- No. 212 prospect46.0 grade
- Side of the ball
- Defense
NFL career
66 regular-season games · 3 seasons as a starter · 29 career approximate value
- Games played
- 66
- Seasons as a starter
- 3
- Career approximate value
- 2966th among USC picks
- AV with the drafting club
- 1966% of career value
- Final season
- 20254 years after the draft
- Accolades
- 1× All-Pro · 1× Pro Bowl
Around pick 180
Who came off the board on either side of Talanoa Hufanga.
App State
Stanford
Clemson
Notre Dame
USC in the 2021 draft
Teammates who went in the same class.
Other S picks from USC
The program's most accomplished players at the same spot.
About this draft profile
Last updated Aug 24, 2026
Talanoa Hufanga in the 2021 NFL Draft
Talanoa Hufanga is a Safety out of USC selected No. 180 overall by the San Francisco 49ers in the 2021 NFL Draft. 66 regular-season games · 3 seasons as a starter · 29 career approximate value USC has produced 252 NFL draft picks since 1980.
Where this data comes from
Pick order and career outcomes come from the nflverse draft archive; position, measurables, and conference at the time of the draft come from the college feed. Career columns stay empty until a player logs regular-season snaps.
Frequently asked questions
Where was Talanoa Hufanga drafted?
Talanoa Hufanga was selected No. 180 overall by the San Francisco 49ers in the 2021 NFL Draft (Rd 5, Pick 36). Full pick detail at https://fantasyhq.co/cfb-hq/draft-history/players/2021/talanoa-hufanga.
What college did Talanoa Hufanga play for?
Talanoa Hufanga played college football at USC in the Pac-12. See every USC draft pick at https://fantasyhq.co/cfb-hq/draft-history/schools/usc-trojans.
How did Talanoa Hufanga's NFL career turn out?
66 regular-season games · 3 seasons as a starter · 29 career approximate value Accolades: 1× All-Pro · 1× Pro Bowl. Career outcome data at https://fantasyhq.co/cfb-hq/draft-history/players/2021/talanoa-hufanga.