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2021 NFL Draft · Rd 7, Pick 16 · #243 overall

James Wiggins Cincinnati Draft

James Wiggins was drafted No. 243 overall by the Arizona Cardinals in the 2021 NFL Draft out of Cincinnati. 3 regular-season games

Overall pick
#243
Round
7
Draft class
2021
NFL games
3

The pick

How James Wiggins came off the board in 2021.

Drafted by

Arizona Cardinals

Rd 7, Pick 16 · #243 overall · NFC West

Full 2021 draft class (259 picks)
Position
Safety S
College
Cincinnati American Athletic at the draft
Measurables
5'11" · 209 lbs
Hometown
Miami, FL
Pre-draft board
No. 224 prospect42.0 grade
Side of the ball
Defense

NFL career

3 regular-season games

Games played
3
Final season
20210 years after the draft

Around pick 243

Who came off the board on either side of James Wiggins.

#241 Mark Webb DB · LAC Georgia #242 Tre Nixon WR · NE UCF #244 Gerrid Doaks RB · MIA Cincinnati #245 Tre Norwood DB · PIT Oklahoma

Cincinnati in the 2021 draft

Teammates who went in the same class.

#110 James Hudson OL · CLE Cincinnati #163 Darrick Forrest S · WAS Cincinnati #244 Gerrid Doaks RB · MIA Cincinnati

Other S picks from Cincinnati

The program's most accomplished players at the same spot.

#62 Bryan Cook S · KC · 2022 Cincinnati #163 Darrick Forrest S · WAS Cincinnati #187 Michael Tyson S · SEA · 2017 Cincinnati

About this draft profile

Last updated Aug 24, 2026

James Wiggins in the 2021 NFL Draft

James Wiggins is a Safety out of Cincinnati selected No. 243 overall by the Arizona Cardinals in the 2021 NFL Draft. 3 regular-season games Cincinnati has produced 74 NFL draft picks since 1980.

Where this data comes from

Pick order and career outcomes come from the nflverse draft archive; position, measurables, and conference at the time of the draft come from the college feed. Career columns stay empty until a player logs regular-season snaps.

Keep exploring

Frequently asked questions

Where was James Wiggins drafted?

James Wiggins was selected No. 243 overall by the Arizona Cardinals in the 2021 NFL Draft (Rd 7, Pick 16). Full pick detail at https://fantasyhq.co/cfb-hq/draft-history/players/2021/james-wiggins.

What college did James Wiggins play for?

James Wiggins played college football at Cincinnati in the American Athletic. See every Cincinnati draft pick at https://fantasyhq.co/cfb-hq/draft-history/schools/cincinnati-bearcats.

How did James Wiggins's NFL career turn out?

3 regular-season games Career outcome data at https://fantasyhq.co/cfb-hq/draft-history/players/2021/james-wiggins.