Ryan Mathews was drafted No. 12 overall by the San Diego Chargers in the 2010 NFL Draft out of Fresno State. 86 regular-season games · 5 seasons as a starter · 44 career approximate value

2010 NFL Draft · Rd 1, Pick 12 · #12 overall

Ryan Mathews Fresno State Draft

Ryan Mathews was drafted No. 12 overall by the San Diego Chargers in the 2010 NFL Draft out of Fresno State. 86 regular-season games · 5 seasons as a starter · 44 career approximate value

1× Pro Bowl

Overall pick
#12
Round
1
Draft class
2010
NFL games
86
Years as starter
5
Career AV
448th at Fresno State
Pro Bowls
1

The pick

How Ryan Mathews came off the board in 2010.

Drafted by

San Diego Chargers

Rd 1, Pick 12 · #12 overall · AFC West

Full 2010 draft class (255 picks)
Position
Running back RB
Measurables
6'0" · 218 lbs
Hometown
Bakersfield, CA
Pre-draft board
No. 26 prospect91.0 grade
Side of the ball
Offense

NFL career

86 regular-season games · 5 seasons as a starter · 44 career approximate value

Games played
86
Seasons as a starter
5
Career approximate value
448th among Fresno State picks
AV with the drafting club
3784% of career value
Final season
20166 years after the draft
Accolades
1× Pro Bowl

Around pick 12

Who came off the board on either side of Ryan Mathews.

Other RB picks from Fresno State

The program's most accomplished players at the same spot.

About this draft profile

Last updated Aug 24, 2026

Ryan Mathews in the 2010 NFL Draft

Ryan Mathews is a Running back out of Fresno State selected No. 12 overall by the San Diego Chargers in the 2010 NFL Draft. 86 regular-season games · 5 seasons as a starter · 44 career approximate value Fresno State has produced 72 NFL draft picks since 1981.

Where this data comes from

Pick order and career outcomes come from the nflverse draft archive; position, measurables, and conference at the time of the draft come from the college feed. Career columns stay empty until a player logs regular-season snaps.

Frequently asked questions

Where was Ryan Mathews drafted?

Ryan Mathews was selected No. 12 overall by the San Diego Chargers in the 2010 NFL Draft (Rd 1, Pick 12). Full pick detail at https://fantasyhq.co/cfb-hq/draft-history/players/2010/ryan-mathews.

What college did Ryan Mathews play for?

Ryan Mathews played college football at Fresno State in the Western Athletic. See every Fresno State draft pick at https://fantasyhq.co/cfb-hq/draft-history/schools/fresno-state-bulldogs.

How did Ryan Mathews's NFL career turn out?

86 regular-season games · 5 seasons as a starter · 44 career approximate value Accolades: 1× Pro Bowl. Career outcome data at https://fantasyhq.co/cfb-hq/draft-history/players/2010/ryan-mathews.