Ko Simpson was drafted No. 105 overall by the Buffalo Bills in the 2006 NFL Draft out of South Carolina. 41 regular-season games · 2 seasons as a starter · 12 career approximate value

2006 NFL Draft · Rd 4, Pick 8 · #105 overall

Ko Simpson South Carolina Draft

Ko Simpson was drafted No. 105 overall by the Buffalo Bills in the 2006 NFL Draft out of South Carolina. 41 regular-season games · 2 seasons as a starter · 12 career approximate value

Overall pick
#105
Round
4
Draft class
2006
NFL games
41
Years as starter
2
Career AV
1242nd at South Carolina

The pick

How Ko Simpson came off the board in 2006.

Drafted by

Buffalo Bills

Rd 4, Pick 8 · #105 overall · AFC East

Full 2006 draft class (255 picks)
Position
Defensive back DB
Measurables
6'1" · 209 lbs
Pre-draft board
No. 60 prospect83.0 grade
Side of the ball
Defense

NFL career

41 regular-season games · 2 seasons as a starter · 12 career approximate value

Games played
41
Seasons as a starter
2
Career approximate value
1242nd among South Carolina picks
AV with the drafting club
1083% of career value
Final season
20093 years after the draft

Around pick 105

Who came off the board on either side of Ko Simpson.

South Carolina in the 2006 draft

Teammates who went in the same class.

Other DB picks from South Carolina

The program's most accomplished players at the same spot.

About this draft profile

Last updated Aug 24, 2026

Ko Simpson in the 2006 NFL Draft

Ko Simpson is a Defensive back out of South Carolina selected No. 105 overall by the Buffalo Bills in the 2006 NFL Draft. 41 regular-season games · 2 seasons as a starter · 12 career approximate value South Carolina has produced 127 NFL draft picks since 1980.

Where this data comes from

Pick order and career outcomes come from the nflverse draft archive; position, measurables, and conference at the time of the draft come from the college feed. Career columns stay empty until a player logs regular-season snaps.

Frequently asked questions

Where was Ko Simpson drafted?

Ko Simpson was selected No. 105 overall by the Buffalo Bills in the 2006 NFL Draft (Rd 4, Pick 8). Full pick detail at https://fantasyhq.co/cfb-hq/draft-history/players/2006/ko-simpson.

What college did Ko Simpson play for?

Ko Simpson played college football at South Carolina in the SEC. See every South Carolina draft pick at https://fantasyhq.co/cfb-hq/draft-history/schools/south-carolina-gamecocks.

How did Ko Simpson's NFL career turn out?

41 regular-season games · 2 seasons as a starter · 12 career approximate value Career outcome data at https://fantasyhq.co/cfb-hq/draft-history/players/2006/ko-simpson.