INDIANA STATE SYCAMORES
INST
3-9
30% win
Final
27 – 55
SOUTHERN ILLINOIS SALUKIS
SIU
7-5
70% win
Win probability
SP+ model
INST 30%
SIU 70%
Pick: SIU
SIU -3.1
O/U 56.0
- Record
- 3-9
- SP+
-
+4.0
- SP+ Off
- 0.0
- SP+ Def
- +0.0
- Record
- 7-5
- SP+
-
+12.7
- SP+ Off
- 0.1
- SP+ Def
- +0.0
Recent head-to-head
INST 4–4 SIU
2024
Wk 9
Wk 9
SIU
17
FINAL
20
W
INST
2023
Wk 12
Wk 12
INST
9
FINAL
38
W
SIU
2021
Wk 11
Wk 11
SIU
W
47
FINAL
21
INST
2019
Wk 10
Wk 10
SIU
W
23
FINAL
14
INST
2018
Wk 8
Wk 8
INST
W
24
FINAL
21
SIU
2017
Wk 8
Wk 8
SIU
W
45
FINAL
24
INST
2016
Wk 8
Wk 8
INST
W
22
FINAL
14
SIU
2015
Wk 7
Wk 7
SIU
36
FINAL
39
W
INST
Recent form
Indiana State Sycamores
vs MUR
@ YSU
vs ILST
@ SDST
@ UND
Southern Illinois Salukis
vs SDAK
vs UNI
Indiana St vs S Illinois — FAQ
Who wins Indiana St vs S Illinois?
FantasyHQ's SP+ model projects Southern Illinois at 70% to win (24.9–31.1) for 2025 CFB Week 6.
What is the Indiana St vs S Illinois predicted score?
Projected score: INST 24.9 – SIU 31.1. Spread model: SIU -3.1; total: O/U 56.0.
When is the Indiana St vs S Illinois game?
Indiana State Sycamores face Southern Illinois Salukis in 2025 CFB Week 6 on Sat, Oct 4 at 7:00 PM ET. Venue: Saluki Stadium.