EASTERN KENTUCKY COLONELS
EKU
5-7
12% win
Final
17 – 51
LOUISVILLE CARDINALS
LOU
9-4
88% win
Win probability
SP+ model
EKU 12%
LOU 88%
Pick: LOU
LOU -7.3
O/U 56.0
- Record
- 5-7
- SP+
-
-11.3
- SP+ Off
- -0.1
- SP+ Def
- +0.0
- Record
- 9-4
- SP+
-
+12.4
- SP+ Off
- 31.6
- SP+ Def
- -19.8
Recent head-to-head
EKU 0–4 LOU
2021
Wk 2
Wk 2
EKU
3
FINAL
30
W
LOU
2019
Wk 2
Wk 2
EKU
0
FINAL
42
W
LOU
2013
Wk 2
Wk 2
EKU
7
FINAL
44
W
LOU
2010
Wk 2
Wk 2
EKU
13
FINAL
23
W
LOU
Recent form
Eastern Kentucky Colonels
@ UTU
vs ACU
vs SUU
@ CARK
vs TAR
Louisville Cardinals
vs UK
@ SMU
vs CLEM
vs CAL
@ VT
E Kentucky vs Cardinals — FAQ
Who wins E Kentucky vs Cardinals?
FantasyHQ's SP+ model projects Louisville at 88% to win (20.7–35.3) for 2025 CFB Week 1.
What is the E Kentucky vs Cardinals predicted score?
Projected score: EKU 20.7 – LOU 35.3. Spread model: LOU -7.3; total: O/U 56.0.
When is the E Kentucky vs Cardinals game?
Eastern Kentucky Colonels face Louisville Cardinals in 2025 CFB Week 1 on Sat, Aug 30 at 3:00 PM ET. Venue: L&N Federal Credit Union Stadium.