SOUTHERN ILLINOIS SALUKIS
SIU
8-5
49% win
Final
47 – 21
SOUTHEAST MISSOURI STATE REDHAWKS
SEMO
4-7
51% win
Win probability
SP+ model
SIU 49%
SEMO 51%
Pick: SEMO
SEMO -0.4
O/U 56.0
- Record
- 8-5
- SP+
-
+4.3
- SP+ Off
- 23.2
- SP+ Def
- -21.8
- Record
- 4-7
- SP+
-
+3.1
- SP+ Off
- 31.1
- SP+ Def
- -29.9
Recent head-to-head
SIU 4–4 SEMO
2025
Wk 4
Wk 4
SIU
W
59
FINAL
31
SEMO
2024
Wk 4
Wk 4
SEMO
W
38
FINAL
21
SIU
2023
Wk 3
Wk 3
SIU
W
26
FINAL
25
SEMO
2022
Wk 2
Wk 2
SEMO
W
34
FINAL
31
SIU
2020
Wk 9
Wk 9
SEMO
17
FINAL
20
W
SIU
2019
Wk 1
Wk 1
SIU
26
FINAL
44
W
SEMO
2018
Wk 3
Wk 3
SEMO
W
48
FINAL
44
SIU
2017
Wk 3
Wk 3
SIU
W
35
FINAL
17
SEMO
Recent form
Southern Illinois Salukis
@ ILST
vs SDAK
@ YSU
@ MUR
vs UNI
Southeast Missouri State Redhawks
vs LIN
@ WIU
@ GWEB
vs CHSO
@ TNTC
S Illinois vs SE Missouri — FAQ
Who wins S Illinois vs SE Missouri?
FantasyHQ's SP+ model projects Southeast Missouri State at 51% to win (27.6–28.4) for 2021 CFB Week 1.
What is the S Illinois vs SE Missouri predicted score?
Projected score: SIU 27.6 – SEMO 28.4. Spread model: SEMO -0.4; total: O/U 56.0.
When is the S Illinois vs SE Missouri game?
Southern Illinois Salukis face Southeast Missouri State Redhawks in 2021 CFB Week 1 on Thu, Sep 2 at 7:30 PM ET. Venue: Houck Field.