Game story
In Week 11 of the 2022 NFL season on 2022-11-21, the San Francisco 49ers took care of business against the Arizona Cardinals, pulling away with a 38–10 final that controlled the game from start to finish.
The highest-scoring period was Q2 with 24 combined points — the stretch that most shaped the final margin.
C. McCoy (Arizona Cardinals) paced the passing game, with -4.74 total EPA, and +3.7% completion percentage over expected.
On the individual side, J. Garoppolo (San Francisco 49ers) delivered the top overall EPA impact at +15.44 — the clearest player-of-the-game signal on the analytics sheet.
The momentum swing (-10.0% win probability) landed in the second quarter when Arizona Cardinals changed the game: (9:42) (No Huddle, Shotgun) 12-C.McCoy pass short middle intended for 6-J.Conner INTERCEPTED by 1-J.Ward at ARI 46. 1-J.Ward to ARI 46 for no gain (6-J.Conner).
Line score
Final score and points by quarter.
| Q1 | Q2 | Q3 | Q4 | — | T | |
|---|---|---|---|---|---|---|
| San Francisco 49ers | 0 | 17 | 14 | 7 | 0 | 38 |
| Arizona Cardinals | 3 | 7 | 0 | 0 | 0 | 10 |
Stars of the game
Top performers by total expected points added (EPA) across passing, rushing, and receiving.
- 1 J. Garoppolo · San Francisco 49ers · Passing · +15.44 total EPA · 30 snaps · +0.51 EPA/play
- 2 G. Kittle · San Francisco 49ers · Receiving · +8.94 total EPA · 6 snaps · +1.49 EPA/play
- 3 D. Hopkins · Arizona Cardinals · Receiving · +5.43 total EPA · 12 snaps · +0.45 EPA/play
- 4 C. McCaffrey · San Francisco 49ers · Receiving · +4.42 total EPA · 7 snaps · +0.63 EPA/play
- 5 G. Dortch · Arizona Cardinals · Receiving · +3.99 total EPA · 10 snaps · +0.40 EPA/play
- 6 B. Aiyuk · San Francisco 49ers · Receiving · +3.37 total EPA · 4 snaps · +0.84 EPA/play
- 7 E. Mitchell · San Francisco 49ers · Rushing · +2.87 total EPA · 9 snaps · +0.32 EPA/play
- 8 D. Samuel · San Francisco 49ers · Receiving · +2.30 total EPA · 9 snaps · +0.26 EPA/play
Player of the game
FantasyHQ analytics player-of-the-game pick based on total EPA and signature plays.
J. Garoppolo — SF · Passing
J. Garoppolo posted the highest total EPA (+15.44) in the game, making the biggest overall impact on San Francisco 49ers's efficiency. Across 30 counted snaps, they averaged +0.51 EPA per play.
The signature play (+4.79 EPA) came from San Francisco 49ers: (8:51) (Shotgun) 10-J.Garoppolo pass deep middle to 85-G.Kittle for 39 yards, TOUCHDOWN.
Who scored touchdowns and field goals
Every touchdown and field goal with the player named in official play-by-play.
Touchdowns
- San Francisco 49ers — B. Aiyuk (J. Garoppolo pass)
- San Francisco 49ers — G. Kittle (J. Garoppolo pass)
- Arizona Cardinals — J. Conner
- San Francisco 49ers — D. Samuel
- San Francisco 49ers — B. Aiyuk (J. Garoppolo pass)
- San Francisco 49ers — G. Kittle (J. Garoppolo pass)
Field goals
- Arizona Cardinals — M. Prater
- San Francisco 49ers — R. Gould
How it unfolded, quarter by quarter
A quarter-by-quarter recap built from live scoring plays and play descriptions.
The opening quarter: Arizona Cardinals won the period 3–0. Arizona Cardinals connected on a field goal from the SF 22 (Q1 53:03) — (8:03) 5-M.Prater 40 yard field goal is GOOD, Center-46-A.Brewer, Holder-14-A.Lee..
The second quarter: San Francisco 49ers won the period 17–7. San Francisco 49ers found the end zone from the ARI 7 (Q2 43:40) — (13:40) (Shotgun) 10-J.Garoppolo pass short middle to 11-B.Aiyuk for 7 yards, TOUCHDOWN.; San Francisco 49ers added 1 points from the ARI 15 (Q2 43:35) — 9-R.Gould extra point is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky.; San Francisco 49ers found the end zone from the ARI 39 (Q2 38:51) — (8:51) (Shotgun) 10-J.Garoppolo pass deep middle to 85-G.Kittle for 39 yards, TOUCHDOWN.; San Francisco 49ers added 1 points from the ARI 15 (Q2 38:42) — 9-R.Gould extra point is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky.; Arizona Cardinals found the end zone from the SF 2 (Q2 34:24) — (4:24) (Shotgun) 6-J.Conner up the middle for 2 yards, TOUCHDOWN.; Arizona Cardinals added 1 points from the SF 15 (Q2 34:19) — 5-M.Prater extra point is GOOD, Center-46-A.Brewer, Holder-14-A.Lee.; San Francisco 49ers connected on a field goal from the ARI 21 (Q2 30:47) — (:47) 9-R.Gould 39 yard field goal is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky..
The third quarter: San Francisco 49ers won the period 14–0. San Francisco 49ers found the end zone from the ARI 39 (Q3 25:44) — (10:44) 19-D.Samuel left end for 39 yards, TOUCHDOWN.; San Francisco 49ers added 1 points from the ARI 15 (Q3 25:34) — 9-R.Gould extra point is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky.; San Francisco 49ers found the end zone from the ARI 13 (Q3 15:33) — (:33) (Shotgun) 10-J.Garoppolo pass short left to 11-B.Aiyuk for 13 yards, TOUCHDOWN.; San Francisco 49ers added 1 points from the ARI 15 (Q3 15:28).
The fourth quarter: San Francisco 49ers won the period 7–0. San Francisco 49ers found the end zone from the ARI 32 (Q4 10:17) — (10:17) 10-J.Garoppolo pass short left to 85-G.Kittle for 32 yards, TOUCHDOWN.; San Francisco 49ers added 1 points from the ARI 15 (Q4 10:08) — 9-R.Gould extra point is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky..
Turning points
Plays that moved win probability the most — the swings that decided the game.
- Arizona Cardinals (Q2 39:42) — (9:42) (No Huddle, Shotgun) 12-C.McCoy pass short middle intended for 6-J.Conner INTERCEPTED by 1-J.Ward at ARI 46. 1-J.Ward to ARI 46 for no gain (6-J.Conner).
- San Francisco 49ers (Q3 25:44) — (10:44) 19-D.Samuel left end for 39 yards, TOUCHDOWN.
- San Francisco 49ers (Q2 43:40) — (13:40) (Shotgun) 10-J.Garoppolo pass short middle to 11-B.Aiyuk for 7 yards, TOUCHDOWN.
- Arizona Cardinals (Q2 36:50) — (6:50) (No Huddle, Shotgun) 12-C.McCoy pass short left to 83-G.Dortch to SF 13 for 47 yards (29-T.Hufanga). Penalty on SF-97-N.Bosa, Defensive Offside, declined.
- San Francisco 49ers (Q2 38:51) — (8:51) (Shotgun) 10-J.Garoppolo pass deep middle to 85-G.Kittle for 39 yards, TOUCHDOWN.
Impact plays
Highest expected-points added snaps that flipped field position and scoring chances.
- San Francisco 49ers (Q2 38:51) — (8:51) (Shotgun) 10-J.Garoppolo pass deep middle to 85-G.Kittle for 39 yards, TOUCHDOWN.
- Arizona Cardinals (Q2 39:42) — (9:42) (No Huddle, Shotgun) 12-C.McCoy pass short middle intended for 6-J.Conner INTERCEPTED by 1-J.Ward at ARI 46. 1-J.Ward to ARI 46 for no gain (6-J.Conner).
- Arizona Cardinals (Q4 2:14) — (2:14) (Shotgun) 19-T.McSorley pass short right intended for 18-A.Green INTERCEPTED by 26-S.Womack at SF -1. Touchback.
- Arizona Cardinals (Q2 36:50) — (6:50) (No Huddle, Shotgun) 12-C.McCoy pass short left to 83-G.Dortch to SF 13 for 47 yards (29-T.Hufanga). Penalty on SF-97-N.Bosa, Defensive Offside, declined.
Quarterback report card
C.McCoy led all passers in efficiency for Arizona Cardinals, setting the tone in the passing game according to FantasyHQ analytics.
- C.McCoy (Arizona Cardinals) · 39 dropbacks · 61.5% completion · +3.7% CPOE · -0.12 EPA/play · -4.74 total EPA
- J.Garoppolo (San Francisco 49ers) · 30 dropbacks · 66.7% completion · +0.4% CPOE · +0.51 EPA/play · +15.44 total EPA
Team stats comparison
Side-by-side offensive and defensive efficiency from FantasyHQ analytics.
| Stat | San Francisco 49ers | Arizona Cardinals |
|---|---|---|
| Offensive EPA/play | +0.298 | -0.122 |
| Offensive success rate | 54.8% | 37.2% |
| Pass EPA/play | +0.515 | -0.144 |
| Rush EPA/play | +0.162 | -0.213 |
| Defensive EPA/play | +0.122 | -0.298 |
| Defensive success rate | 62.8% | 45.2% |
By the numbers
Despite the final score, San Francisco 49ers generated the better offensive EPA per play (+0.30 vs -0.12), suggesting they moved the ball more efficiently.
- Arizona Cardinals: 11 drives, -10.50 total EPA, 2 scoring drives
- San Francisco 49ers: 11 drives, +21.76 total EPA, 6 scoring drives
Key takeaways
What to remember for fantasy research, film review, and follow-up box score digging.
- San Francisco 49ers leaves with the win and the better postgame narrative for Week-to-week momentum.
- J. Garoppolo (San Francisco 49ers) is the first name to pull up for highlight reels and prop-retrospective research.
- C. McCoy (ARI) beat expectation through the air — positive CPOE game for stack builds.
Every scoring play
Chronological scoring with field position and full play-by-play context.
- Arizona Cardinals FG (+3) — Q1 53:03 · SF 22 · Score 0-3
(8:03) 5-M.Prater 40 yard field goal is GOOD, Center-46-A.Brewer, Holder-14-A.Lee. - San Francisco 49ers TD (+6) — Q2 43:40 · ARI 7 · Score 6-3
(13:40) (Shotgun) 10-J.Garoppolo pass short middle to 11-B.Aiyuk for 7 yards, TOUCHDOWN. - San Francisco 49ers XP (+1) — Q2 43:35 · ARI 15 · Score 7-3
9-R.Gould extra point is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky. - San Francisco 49ers TD (+6) — Q2 38:51 · ARI 39 · Score 13-3
(8:51) (Shotgun) 10-J.Garoppolo pass deep middle to 85-G.Kittle for 39 yards, TOUCHDOWN. - San Francisco 49ers XP (+1) — Q2 38:42 · ARI 15 · Score 14-3
9-R.Gould extra point is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky. - Arizona Cardinals TD (+6) — Q2 34:24 · SF 2 · Score 14-9
(4:24) (Shotgun) 6-J.Conner up the middle for 2 yards, TOUCHDOWN. - Arizona Cardinals XP (+1) — Q2 34:19 · SF 15 · Score 14-10
5-M.Prater extra point is GOOD, Center-46-A.Brewer, Holder-14-A.Lee. - San Francisco 49ers FG (+3) — Q2 30:47 · ARI 21 · Score 17-10
(:47) 9-R.Gould 39 yard field goal is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky. - San Francisco 49ers TD (+6) — Q3 25:44 · ARI 39 · Score 23-10
(10:44) 19-D.Samuel left end for 39 yards, TOUCHDOWN. - San Francisco 49ers XP (+1) — Q3 25:34 · ARI 15 · Score 24-10
9-R.Gould extra point is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky. - San Francisco 49ers TD (+6) — Q3 15:33 · ARI 13 · Score 30-10
(:33) (Shotgun) 10-J.Garoppolo pass short left to 11-B.Aiyuk for 13 yards, TOUCHDOWN. - San Francisco 49ers XP (+1) — Q3 15:28 · ARI 15 · Score 31-10
9-R.Gould extra point is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky. PENALTY on ARI, Illegal Formation, 5 yards, enforced between downs. - San Francisco 49ers TD (+6) — Q4 10:17 · ARI 32 · Score 37-10
(10:17) 10-J.Garoppolo pass short left to 85-G.Kittle for 32 yards, TOUCHDOWN. - San Francisco 49ers XP (+1) — Q4 10:08 · ARI 15 · Score 38-10
9-R.Gould extra point is GOOD, Center-46-T.Pepper, Holder-18-M.Wishnowsky.
Frequently asked questions
Who won San Francisco 49ers vs Arizona Cardinals?
The San Francisco 49ers beat the Arizona Cardinals 38-10 in Week 11, 2022 on 2022-11-21.
What was the final score of San Francisco 49ers vs Arizona Cardinals?
The final score was San Francisco 49ers 38, Arizona Cardinals 10 (SF 38-10 ARI) in Week 11, 2022 on 2022-11-21.
What was the score by quarter in San Francisco 49ers vs Arizona Cardinals?
Q1: San Francisco 49ers 0, Arizona Cardinals 3; Q2: San Francisco 49ers 17, Arizona Cardinals 7; Q3: San Francisco 49ers 14, Arizona Cardinals 0; Q4: San Francisco 49ers 7, Arizona Cardinals 0; Final: San Francisco 49ers 38, Arizona Cardinals 10.
Who scored touchdowns and field goals in San Francisco 49ers vs Arizona Cardinals?
San Francisco 49ers touchdown — B. Aiyuk (J. Garoppolo pass) (Q2 43:40) San Francisco 49ers touchdown — G. Kittle (J. Garoppolo pass) (Q2 38:51) Arizona Cardinals touchdown — J. Conner (Q2 34:24) San Francisco 49ers touchdown — D. Samuel (Q3 25:44) San Francisco 49ers touchdown — B. Aiyuk (J. Garoppolo pass) (Q3 15:33) San Francisco 49ers touchdown — G. Kittle (J. Garoppolo pass) (Q4 10:17) Arizona Cardinals field goal — M. Prater (Q1 53:03, 3 pts) San Francisco 49ers field goal — R. Gould (Q2 30:47, 3 pts) Extra points followed each touchdown unless noted in the play-by-play.
How did the quarterbacks play in San Francisco 49ers vs Arizona Cardinals?
C. McCoy (Arizona Cardinals), 61.5% completion, +3.7% CPOE, -0.12 EPA per dropback, -4.74 total passing EPA. J. Garoppolo (San Francisco 49ers), 66.7% completion, +0.4% CPOE, +0.51 EPA per dropback, +15.44 total passing EPA.
Who was the most impactful player in San Francisco 49ers vs Arizona Cardinals?
J. Garoppolo (San Francisco 49ers) led the game in total EPA with +15.44 on passing plays. across 30 snaps. The top single-play swing was (+4.79 EPA): (8:51) (Shotgun) 10-J.Garoppolo pass deep middle to 85-G.Kittle for 39 yards, TOUCHDOWN.. The biggest win-probability swing was -10.0%.
Season records after this game
San Francisco 49ers
Entered 5-4 Now 6-4 W
Arizona Cardinals
Entered 4-6 Now 4-7 L