Isaiah McGuire was drafted No. 126 overall by the Cleveland Browns in the 2023 NFL Draft out of Missouri. 37 regular-season games · 7 career approximate value
2023 NFL Draft · Rd 4, Pick 24 · #126 overall
Isaiah McGuire Missouri Draft
Isaiah McGuire was drafted No. 126 overall by the Cleveland Browns in the 2023 NFL Draft out of Missouri. 37 regular-season games · 7 career approximate value
- Overall pick
- #126
- Round
- 4
- Draft class
- 2023
- NFL games
- 37
- Career AV
- 741st at Missouri
The pick
How Isaiah McGuire came off the board in 2023.
- Position
- Defensive lineman DL
- College
-
Missouri
SEC at the draft
- Measurables
- 6'4" · 268 lbs
- Hometown
- Tulsa, OK
- Pre-draft board
- No. 174 prospect52.0 grade
- Side of the ball
- Defense
NFL career
37 regular-season games · 7 career approximate value
- Games played
- 37
- Career approximate value
- 741st among Missouri picks
- AV with the drafting club
- 7100% of career value
- Final season
- 20252 years after the draft
Around pick 126
Who came off the board on either side of Isaiah McGuire.
Ole Miss
TCU
Fresno State
Georgia
Other DL picks from Missouri
The program's most accomplished players at the same spot.
About this draft profile
Last updated Aug 24, 2026
Isaiah McGuire in the 2023 NFL Draft
Isaiah McGuire is a Defensive lineman out of Missouri selected No. 126 overall by the Cleveland Browns in the 2023 NFL Draft. 37 regular-season games · 7 career approximate value Missouri has produced 108 NFL draft picks since 1980.
Where this data comes from
Pick order and career outcomes come from the nflverse draft archive; position, measurables, and conference at the time of the draft come from the college feed. Career columns stay empty until a player logs regular-season snaps.
Frequently asked questions
Where was Isaiah McGuire drafted?
Isaiah McGuire was selected No. 126 overall by the Cleveland Browns in the 2023 NFL Draft (Rd 4, Pick 24). Full pick detail at https://fantasyhq.co/cfb-hq/draft-history/players/2023/isaiah-mcguire.
What college did Isaiah McGuire play for?
Isaiah McGuire played college football at Missouri in the SEC. See every Missouri draft pick at https://fantasyhq.co/cfb-hq/draft-history/schools/missouri-tigers.
How did Isaiah McGuire's NFL career turn out?
37 regular-season games · 7 career approximate value Career outcome data at https://fantasyhq.co/cfb-hq/draft-history/players/2023/isaiah-mcguire.