Isaiah McDuffie was drafted No. 220 overall by the Green Bay Packers in the 2021 NFL Draft out of Boston College. 80 regular-season games · 2 seasons as a starter · 19 career approximate value
2021 NFL Draft · Rd 6, Pick 36 · #220 overall
Isaiah McDuffie Boston College Draft
Isaiah McDuffie was drafted No. 220 overall by the Green Bay Packers in the 2021 NFL Draft out of Boston College. 80 regular-season games · 2 seasons as a starter · 19 career approximate value
- Overall pick
- #220
- Round
- 6
- Draft class
- 2021
- NFL games
- 80
- Years as starter
- 2
- Career AV
- 1944th at Boston College
The pick
How Isaiah McDuffie came off the board in 2021.
- Position
- Linebacker LB
- College
-
Boston College
ACC at the draft
- Measurables
- 6'1" · 227 lbs
- Hometown
- Buffalo, NY
- Pre-draft board
- No. 257 prospect36.0 grade
- Side of the ball
- Defense
NFL career
80 regular-season games · 2 seasons as a starter · 19 career approximate value
- Games played
- 80
- Seasons as a starter
- 2
- Career approximate value
- 1944th among Boston College picks
- AV with the drafting club
- 19100% of career value
- Final season
- 20254 years after the draft
Around pick 220
Who came off the board on either side of Isaiah McDuffie.
Texas
Auburn
North Carolina
Alabama
Boston College in the 2021 draft
Teammates who went in the same class.
Other LB picks from Boston College
The program's most accomplished players at the same spot.
Luke Kuechly
LB · CAR · 2012
Boston College · Hall of Fame · 5× All-Pro · 7× Pro Bowl
#80
Bill Romanowski
LB · SF · 1988
Boston College · 2× Pro Bowl
#141
Stephen Boyd
LB · DET · 1995
Boston College · 2× Pro Bowl
#163
Matt Milano
LB · BUF · 2017
Boston College · 1× All-Pro · 1× Pro Bowl
#110
Steve DeOssie
LB · DAL · 1984
Boston College
#132
Kevin Pierre-Louis
LB · SEA · 2014
Boston College
About this draft profile
Last updated Aug 24, 2026
Isaiah McDuffie in the 2021 NFL Draft
Isaiah McDuffie is a Linebacker out of Boston College selected No. 220 overall by the Green Bay Packers in the 2021 NFL Draft. 80 regular-season games · 2 seasons as a starter · 19 career approximate value Boston College has produced 117 NFL draft picks since 1980.
Where this data comes from
Pick order and career outcomes come from the nflverse draft archive; position, measurables, and conference at the time of the draft come from the college feed. Career columns stay empty until a player logs regular-season snaps.
Frequently asked questions
Where was Isaiah McDuffie drafted?
Isaiah McDuffie was selected No. 220 overall by the Green Bay Packers in the 2021 NFL Draft (Rd 6, Pick 36). Full pick detail at https://fantasyhq.co/cfb-hq/draft-history/players/2021/isaiah-mcduffie.
What college did Isaiah McDuffie play for?
Isaiah McDuffie played college football at Boston College in the ACC. See every Boston College draft pick at https://fantasyhq.co/cfb-hq/draft-history/schools/boston-college-eagles.
How did Isaiah McDuffie's NFL career turn out?
80 regular-season games · 2 seasons as a starter · 19 career approximate value Career outcome data at https://fantasyhq.co/cfb-hq/draft-history/players/2021/isaiah-mcduffie.